Matches in SemOpenAlex for { <https://semopenalex.org/work/W2340712601> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2340712601 endingPage "C1325" @default.
- W2340712601 startingPage "C1319" @default.
- W2340712601 abstract "Volume regulation of C6 glioma cells was studied while the bath osmolality was reduced from 300 to 150 mosmol/kg. Exposure to a hyposmotic challenge elicited a typical regulatory volume decrease (RVD). No regulatory volume increase was observed upon restoration of isosmotic conditions. During a second subsequent hyposmotic challenge, the cells did not respond with RVD. High extracellular K+ concentration and the K+ channel blockers Ba2+ and quinine inhibited the RVD. RVD was abolished after Cl- was replaced by gluconate and by the Cl- channel blocker 5-nitro-2(3-phenylpropylamino)benzoic acid. Amino acid (AA) concentration in cell and perfusate was determined. In control, cell content was only 26 mmol/l. Hypotonicity increased the efflux of AA from 0.14 to 0.60 mmol/min. During the second hyposmotic challenge, the release was 0.32 mmol/min. The data show that C6 cells adjust their volume under hyposmotic conditions but lose the ability to restore their volume during a subsequent hyposmotic treatment. K+ and Cl- are the main osmolytes involved in volume adjustment through conductive pathways. AA do not contribute substantially to cell volume regulation." @default.
- W2340712601 created "2016-06-24" @default.
- W2340712601 creator A5010744027 @default.
- W2340712601 creator A5035244507 @default.
- W2340712601 creator A5049470940 @default.
- W2340712601 date "1996-05-01" @default.
- W2340712601 modified "2023-10-14" @default.
- W2340712601 title "Volume regulation in rat brain glial cells: lack of a substantial contribution of free amino acids" @default.
- W2340712601 cites W1965138408 @default.
- W2340712601 cites W1971808811 @default.
- W2340712601 cites W1975777248 @default.
- W2340712601 cites W1982632034 @default.
- W2340712601 cites W1990918868 @default.
- W2340712601 cites W1993737892 @default.
- W2340712601 cites W1995975222 @default.
- W2340712601 cites W2001568860 @default.
- W2340712601 cites W2034153487 @default.
- W2340712601 cites W2040740610 @default.
- W2340712601 cites W2076707026 @default.
- W2340712601 cites W2083067051 @default.
- W2340712601 doi "https://doi.org/10.1152/ajpcell.1996.270.5.c1319" @default.
- W2340712601 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8967431" @default.
- W2340712601 hasPublicationYear "1996" @default.
- W2340712601 type Work @default.
- W2340712601 sameAs 2340712601 @default.
- W2340712601 citedByCount "14" @default.
- W2340712601 crossrefType "journal-article" @default.
- W2340712601 hasAuthorship W2340712601A5010744027 @default.
- W2340712601 hasAuthorship W2340712601A5035244507 @default.
- W2340712601 hasAuthorship W2340712601A5049470940 @default.
- W2340712601 hasConcept C12554922 @default.
- W2340712601 hasConcept C126322002 @default.
- W2340712601 hasConcept C127160389 @default.
- W2340712601 hasConcept C129900496 @default.
- W2340712601 hasConcept C134018914 @default.
- W2340712601 hasConcept C145822097 @default.
- W2340712601 hasConcept C153461711 @default.
- W2340712601 hasConcept C185592680 @default.
- W2340712601 hasConcept C200082930 @default.
- W2340712601 hasConcept C28406088 @default.
- W2340712601 hasConcept C515207424 @default.
- W2340712601 hasConcept C519063684 @default.
- W2340712601 hasConcept C55493867 @default.
- W2340712601 hasConcept C71924100 @default.
- W2340712601 hasConcept C86803240 @default.
- W2340712601 hasConceptScore W2340712601C12554922 @default.
- W2340712601 hasConceptScore W2340712601C126322002 @default.
- W2340712601 hasConceptScore W2340712601C127160389 @default.
- W2340712601 hasConceptScore W2340712601C129900496 @default.
- W2340712601 hasConceptScore W2340712601C134018914 @default.
- W2340712601 hasConceptScore W2340712601C145822097 @default.
- W2340712601 hasConceptScore W2340712601C153461711 @default.
- W2340712601 hasConceptScore W2340712601C185592680 @default.
- W2340712601 hasConceptScore W2340712601C200082930 @default.
- W2340712601 hasConceptScore W2340712601C28406088 @default.
- W2340712601 hasConceptScore W2340712601C515207424 @default.
- W2340712601 hasConceptScore W2340712601C519063684 @default.
- W2340712601 hasConceptScore W2340712601C55493867 @default.
- W2340712601 hasConceptScore W2340712601C71924100 @default.
- W2340712601 hasConceptScore W2340712601C86803240 @default.
- W2340712601 hasIssue "5" @default.
- W2340712601 hasLocation W23407126011 @default.
- W2340712601 hasLocation W23407126012 @default.
- W2340712601 hasOpenAccess W2340712601 @default.
- W2340712601 hasPrimaryLocation W23407126011 @default.
- W2340712601 hasRelatedWork W1816636001 @default.
- W2340712601 hasRelatedWork W1974390393 @default.
- W2340712601 hasRelatedWork W1977793137 @default.
- W2340712601 hasRelatedWork W1993834888 @default.
- W2340712601 hasRelatedWork W2057038354 @default.
- W2340712601 hasRelatedWork W2062722270 @default.
- W2340712601 hasRelatedWork W2080586001 @default.
- W2340712601 hasRelatedWork W2132125134 @default.
- W2340712601 hasRelatedWork W2337878855 @default.
- W2340712601 hasRelatedWork W2415279685 @default.
- W2340712601 hasVolume "270" @default.
- W2340712601 isParatext "false" @default.
- W2340712601 isRetracted "false" @default.
- W2340712601 magId "2340712601" @default.
- W2340712601 workType "article" @default.