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- W2340803765 abstract "PYROMEN is a sterile, nonprotein, nonana-phylactogenic extract of Pseudomonas aemginosa and Proteus vulgaris prepared as a colloidal dispersion in normal saline for intravenous use.1 , 2 Pharmacologically, it is a pyrogen of a high degree of reliability and a low order of toxicity. Chemical analysis has identified it as a complex polysaccharide.1 2 3 4 Study of the histologie and physiologic effects in animals revealed some ACTH-like effects.3 4 5 6 Clinical evaluation was directed toward its efficacy not only as a pyrexial agent but also as a stimulant of the pituitary-adrenal axis in those diseases believed to respond to ACTH.7 8 9 10 11 In certain allergic states it proved beneficial . . ." @default.
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- W2340803765 date "1951-12-20" @default.
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- W2340803765 title "The Effects of Pyromen Administered Intravenously in Subpyrexial Doses to Depressed Patients" @default.
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- W2340803765 doi "https://doi.org/10.1056/nejm195112202452502" @default.
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