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- W2340970135 abstract "INTRODUCTION: Pseudomonas aeruginosa is one of the most prevalent bacterial strains in a clinical environment, responsible for 30% of nosocomial pneumonia cases occurring in intubated and mechanically ventilated patients [1]. Colonization of the intubation device leads to mortality for over 40% of these cases, despite aggressive antibiotic therapy. Therefore, a strategy to reduce bacterial adhesion to intubation tubes is desirable. We are developing an approach based on the surface modification of the polymer used for this application, medical grade poly(vinyl chloride) (PVC). This paper investigates a method to prevent protein adsorption and eventual bacterial adhesion, as protein adhesion is believed to be a key event responsible for specific adhesion of bacteria to a surface. The strategy is to mask the PVC substrate with a chemically inert Teflon-like fluoropolymer layer, which serves as an ideal platform for further surface modification due to its low surface energy properties[2]. By exploiting hydrophobic" @default.
- W2340970135 created "2016-06-24" @default.
- W2340970135 creator A5075432419 @default.
- W2340970135 date "2002-01-01" @default.
- W2340970135 modified "2023-09-27" @default.
- W2340970135 title "SURFACE MODIFICATION OF POLY(VINYL CHLORIDE) INTUBATION TUBES TO CONTROL BACTERIAL ADHESION : TEFLON-LIKE AND PLURONICS ®" @default.
- W2340970135 hasPublicationYear "2002" @default.
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