Matches in SemOpenAlex for { <https://semopenalex.org/work/W2340986070> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2340986070 abstract "A B S T R A C T A convenient, specific, precise, and reproducible radioimmunoassay system for measurement of triiodothyronine (Ta) in human serum has been developed. The procedure compares the ability of standards and unknowns to compete with radioactive Ta for binding sites on a Ts-binding antiserum produced in rabbits by immunization with human thyroglobulin. The assay is set up in the presence of 250 ng thyroxine (T4) in all tubes, to mobilize T3 from its binding with the thyronine-binding globulin (TBG), and athyreotic sheep serum in standards to correct for the TBG in the unknowns. The method regularly detected 0.4 ng Ts, which would correspond to a Ts concentration of 100 ng/100 ml when 400 ;I of serum is analyzed. The mean recovery of unlabeled Ta added to normal serum pools was 106%. Serial dilution of hyperthyroid sera containing high concentrations of Ta with athyreotic sheep serum yielded expected values. The serum T3 concentration in 80% of 31 euthyroid normal subjects was less than 100 ng/100 ml (range < 100-170 ng/100 ml); it was greater than 170 ng/100 ml in 89% of 27 sera of hyperthyroid patients with untreated Graves' disease (range < 100-1300, mean 519 in 25 sera with detectable Ta). The concentration of serum Ta fell, frequently to undetectable levels, during treatment of hyperthyroid patients with antithyroid drugs. The serum Ta concentration in four hypothyroid patients was less than 100 ng/100 ml." @default.
- W2340986070 created "2016-06-24" @default.
- W2340986070 creator A5009773473 @default.
- W2340986070 creator A5068304636 @default.
- W2340986070 creator A5089698368 @default.
- W2340986070 date "1971-01-01" @default.
- W2340986070 modified "2023-09-23" @default.
- W2340986070 title "in Human Serum" @default.
- W2340986070 cites W1979904200 @default.
- W2340986070 cites W1985685797 @default.
- W2340986070 cites W2006457802 @default.
- W2340986070 cites W2013426106 @default.
- W2340986070 cites W2013915034 @default.
- W2340986070 cites W2022350011 @default.
- W2340986070 cites W2041160265 @default.
- W2340986070 cites W2041799792 @default.
- W2340986070 cites W2042157916 @default.
- W2340986070 cites W2078292462 @default.
- W2340986070 cites W2080806531 @default.
- W2340986070 cites W2088060890 @default.
- W2340986070 cites W2095811126 @default.
- W2340986070 cites W2109880659 @default.
- W2340986070 cites W2135957727 @default.
- W2340986070 cites W2302026003 @default.
- W2340986070 cites W2442403000 @default.
- W2340986070 cites W2461471600 @default.
- W2340986070 hasPublicationYear "1971" @default.
- W2340986070 type Work @default.
- W2340986070 sameAs 2340986070 @default.
- W2340986070 citedByCount "2" @default.
- W2340986070 crossrefType "journal-article" @default.
- W2340986070 hasAuthorship W2340986070A5009773473 @default.
- W2340986070 hasAuthorship W2340986070A5068304636 @default.
- W2340986070 hasAuthorship W2340986070A5089698368 @default.
- W2340986070 hasConcept C126322002 @default.
- W2340986070 hasConcept C134018914 @default.
- W2340986070 hasConcept C159654299 @default.
- W2340986070 hasConcept C176685330 @default.
- W2340986070 hasConcept C185592680 @default.
- W2340986070 hasConcept C203014093 @default.
- W2340986070 hasConcept C2777195454 @default.
- W2340986070 hasConcept C2778288131 @default.
- W2340986070 hasConcept C2778835679 @default.
- W2340986070 hasConcept C3020081911 @default.
- W2340986070 hasConcept C526584372 @default.
- W2340986070 hasConcept C71924100 @default.
- W2340986070 hasConcept C81358767 @default.
- W2340986070 hasConcept C91523082 @default.
- W2340986070 hasConceptScore W2340986070C126322002 @default.
- W2340986070 hasConceptScore W2340986070C134018914 @default.
- W2340986070 hasConceptScore W2340986070C159654299 @default.
- W2340986070 hasConceptScore W2340986070C176685330 @default.
- W2340986070 hasConceptScore W2340986070C185592680 @default.
- W2340986070 hasConceptScore W2340986070C203014093 @default.
- W2340986070 hasConceptScore W2340986070C2777195454 @default.
- W2340986070 hasConceptScore W2340986070C2778288131 @default.
- W2340986070 hasConceptScore W2340986070C2778835679 @default.
- W2340986070 hasConceptScore W2340986070C3020081911 @default.
- W2340986070 hasConceptScore W2340986070C526584372 @default.
- W2340986070 hasConceptScore W2340986070C71924100 @default.
- W2340986070 hasConceptScore W2340986070C81358767 @default.
- W2340986070 hasConceptScore W2340986070C91523082 @default.
- W2340986070 hasLocation W23409860701 @default.
- W2340986070 hasOpenAccess W2340986070 @default.
- W2340986070 hasPrimaryLocation W23409860701 @default.
- W2340986070 hasRelatedWork W114869524 @default.
- W2340986070 hasRelatedWork W1894396846 @default.
- W2340986070 hasRelatedWork W1903033769 @default.
- W2340986070 hasRelatedWork W1927253507 @default.
- W2340986070 hasRelatedWork W1976552080 @default.
- W2340986070 hasRelatedWork W1979387660 @default.
- W2340986070 hasRelatedWork W1987542619 @default.
- W2340986070 hasRelatedWork W2026360835 @default.
- W2340986070 hasRelatedWork W2049208157 @default.
- W2340986070 hasRelatedWork W2064782783 @default.
- W2340986070 hasRelatedWork W2074150207 @default.
- W2340986070 hasRelatedWork W2105460809 @default.
- W2340986070 hasRelatedWork W2120681566 @default.
- W2340986070 hasRelatedWork W2125758059 @default.
- W2340986070 hasRelatedWork W2323776607 @default.
- W2340986070 hasRelatedWork W2332297695 @default.
- W2340986070 hasRelatedWork W2396822161 @default.
- W2340986070 hasRelatedWork W2403062108 @default.
- W2340986070 hasRelatedWork W2444664394 @default.
- W2340986070 hasRelatedWork W2463065918 @default.
- W2340986070 isParatext "false" @default.
- W2340986070 isRetracted "false" @default.
- W2340986070 magId "2340986070" @default.
- W2340986070 workType "article" @default.