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- W2341001743 abstract "The cancer chemopreventive potential of sarcophine-diol in a chemical carcinogen initiation–promotion experimental tumor model in mice was evaluated. Sarcophine-diol, when given orally, afforded significant protection in the mouse skin cancer model initiated by the topical administration of (±)-( E)-4-methyl-2-[( E)-hydroxyamino]-5-nitro-6-methoxy-3-hexanamide (NOR-1) and promoted by 12- O-tetradecanoylphorbol-13-acetate (TPA). These findings, along with our initial reports, suggest that sarcophine-diol is an effective cancer chemopreventive agent, even when administered orally and at a very low dose and thus indicating possible potential human applications in the control of malignancy." @default.
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- W2341001743 date "2013-02-01" @default.
- W2341001743 modified "2023-10-16" @default.
- W2341001743 title "Chemopreventive Effect of Sarcophine-diol on NOR-1-Induced TPA-Promoted Skin Carcinogenesis in Female HOS:HR-1 Mice" @default.
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- W2341001743 doi "https://doi.org/10.1177/1934578x1300800203" @default.
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