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- W2341076466 abstract "Objective: cystic fibrosis has become, in the last 70 years, the most important potentially fatal inherited disease that affects white individuals around the world. Although it is considered a genetic disorder, which strikes cells of different organs, not all patients present similar clinical response. Many clinical manifestations, mainly pulmonary and gastrointestinal, may develop in cystic fibrosis patients. The aim of this article is to offer pediatricians an updated review of the controversies and recent advances in the treatment of cystic fibrosis. Sources: systematic review in the Medline database. Summary of the findings: seventy-nine articles about cystic fibrosis published in international journals were reviewed. This article presents an updated and critical review of the main events related to the incidence, pathophysiology, diagnosis and treatment of cystic fibrosis. Conclusions: even though no treatment is available for this disease, new findings about its etiology and pathophysiology have been discovered in the last two decades, improving treatment and survival of cystic fibrosis patients." @default.
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- W2341076466 date "2002-01-01" @default.
- W2341076466 modified "2023-09-25" @default.
- W2341076466 title "Controvérsias na fibrose cística - do pediatra ao especialista Controversies in cystic fibrosis - from pediatrician to specialist" @default.
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