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- W2341094715 abstract "The 1,2-aminoindanol scaffold has been found to be very efficient, enhancing the enantioselectivity when present in organocatalysts. This may be explained by its ability to induce a bifunctional activation of the substrates involved in the reaction. Thus, it is easy to find hydrogen-bonding organocatalysts ((thio)ureas, squaramides, quinolinium thioamide, etc.) in the literature containing this favored structural core. They have been successfully employed in reactions such as Friedel–Crafts alkylation, Michael addition, Diels–Alder and aza-Henry reactions. However, the 1,2-aminoindanol core incorporated into proline derivatives has been scarcely explored. Herein, the most representative and illustrative examples are compiled and this review will be mainly focused on the cases where the aminoindanol moiety confers bifunctionality to the organocatalysts." @default.
- W2341094715 created "2016-06-24" @default.
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- W2341094715 creator A5050525191 @default.
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- W2341094715 date "2016-03-14" @default.
- W2341094715 modified "2023-09-30" @default.
- W2341094715 title "The aminoindanol core as a key scaffold in bifunctional organocatalysts" @default.
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- W2341094715 doi "https://doi.org/10.3762/bjoc.12.50" @default.
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