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• W2341194689 abstract "ResumoDiferente de outros paises de Europa e America do Norte, no Brasil, estudos sobre o perfil comportamental de pacientes com sindrome de Noonan (SN) sao inexistentes. O objetivo do estudo foi tracar o perfil de funcionamento comportamental de 10 participantes (quatro do sexo feminino e seis do sexo masculino, sendo 8 adultos e 2 criancas), com mutacao do gene PTPN11, compativel com a SN. Para isso, foram utilizados o Inventario de Comportamentos de Criancas e Adolescentes de 6 a 18 anos (CBCL/ 6-18) e o Inventario de Auto-Avaliacao para Adultos de 18 a 59 anos (ASR). Os principais resultados apontam que na Escala de Funcionamento Adaptativo todos os participantes encontram-se na faixa de normalidade. Na Escala das Sindromes, os participantes adultos situam-se na normalidade e as criancas apresentam problemas, na faixa clinica, referentes as sub-escalas ansiedade/depressao, queixas somaticas e comportamento agressivo. Na AbstractDifferent from other countries of Europe and North American, studies about the behavioral profile of Noonan syndrome's patients are inexistent. The objective of this study was to report the profiles of behavioral functions of 10 participants (4 females and 6 males), with mutations in the PTPN11 gene. For this assessment it was used the Inventory of Behaviors of Children and Adolescents from 6 to 18 years (CBCL/6-18) and the Inventory of Auto-Evaluation for Adults from 18 to 59 years (ASR). The main results point that in Adaptive Functioning Scale all the participants were in the normality range. In the Syndrome Scale the adult participants were in normality range and the children were in clinical range to the sub-scales anxious/depressed, somatic complaints and aggressive behavior. In the DSM-Oriented Scale, 25% of the adult patients were in the borderline clinical range and clinical range, respectively, for Avoidant Personality" @default.
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• W2341194689 date "2010-01-01" @default.
• W2341194689 modified "2023-09-26" @default.
• W2341194689 title "Alterações comportamentais na Síndrome de Noonan: dados preliminares brasileiros Behavioral disturbances in Noonan Syndrome: Brazilian preliminary data" @default.
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