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• W2341236723 endingPage "e0154279" @default.
• W2341236723 startingPage "e0154279" @default.
• W2341236723 abstract "Small RNAs (smRNAs) control a variety of cellular processes by silencing target genes at the transcriptional or post-transcription level. While extensively studied in plants, relatively little is known about smRNAs and their targets in marine phytoplankton, such as Emiliania huxleyi (E. huxleyi). Deep sequencing was performed of smRNAs extracted at different time points as E. huxleyi cells transition from logarithmic to stationary phase growth in batch culture. Computational analyses predicted 18 E. huxleyi specific miRNAs. The 18 miRNA candidates and their precursors vary in length (18–24 nt and 71–252 nt, respectively), genome copy number (3–1,459), and the number of genes targeted (2–107). Stem-loop real time reverse transcriptase (RT) PCR was used to validate miRNA expression which varied by nearly three orders of magnitude when growth slows and cells enter stationary phase. Stem-loop RT PCR was also used to examine the expression profiles of miRNA in calcifying and non-calcifying cultures, and a small subset was found to be differentially expressed when nutrients become limiting and calcification is enhanced. In addition to miRNAs, endogenous small RNAs such as ra-siRNAs, ta-siRNAs, nat-siRNAs, and piwiRNAs were predicted along with the machinery for the biogenesis and processing of si-RNAs. This study is the first genome-wide investigation smRNAs pathways in E. huxleyi. Results provide new insights into the importance of smRNAs in regulating aspects of physiological growth and adaptation in marine phytoplankton and further challenge the notion that smRNAs evolved with multicellularity, expanding our perspective of these ancient regulatory pathways." @default.
• W2341236723 created "2016-06-24" @default.
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• W2341236723 date "2016-04-21" @default.
• W2341236723 modified "2023-09-27" @default.
• W2341236723 title "Characterization of the Small RNA Transcriptome of the Marine Coccolithophorid, Emiliania huxleyi" @default.
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• W2341236723 cites W1581610755 @default.
• W2341236723 cites W1608587128 @default.
• W2341236723 cites W1965431589 @default.
• W2341236723 cites W1968410036 @default.
• W2341236723 cites W1975049967 @default.
• W2341236723 cites W1979154939 @default.
• W2341236723 cites W1984780475 @default.
• W2341236723 cites W1990015734 @default.
• W2341236723 cites W1995654442 @default.
• W2341236723 cites W2001010223 @default.
• W2341236723 cites W2007318995 @default.
• W2341236723 cites W2011269750 @default.
• W2341236723 cites W2011440727 @default.
• W2341236723 cites W2016112105 @default.
• W2341236723 cites W2017356274 @default.
• W2341236723 cites W2019205466 @default.
• W2341236723 cites W2020441317 @default.
• W2341236723 cites W2021905258 @default.
• W2341236723 cites W2022194054 @default.
• W2341236723 cites W2022916922 @default.
• W2341236723 cites W2024316824 @default.
• W2341236723 cites W2026222098 @default.
• W2341236723 cites W2027279590 @default.
• W2341236723 cites W2036649644 @default.
• W2341236723 cites W2038008886 @default.
• W2341236723 cites W2039242709 @default.
• W2341236723 cites W2040768064 @default.
• W2341236723 cites W2046109186 @default.
• W2341236723 cites W2050386030 @default.
• W2341236723 cites W2057377177 @default.
• W2341236723 cites W2085742435 @default.
• W2341236723 cites W2091163647 @default.
• W2341236723 cites W2091922579 @default.
• W2341236723 cites W2092501114 @default.
• W2341236723 cites W2092758029 @default.
• W2341236723 cites W2097703411 @default.
• W2341236723 cites W2098085279 @default.
• W2341236723 cites W2098530244 @default.
• W2341236723 cites W2098566939 @default.
• W2341236723 cites W2099660828 @default.
• W2341236723 cites W2103903744 @default.
• W2341236723 cites W2111401971 @default.
• W2341236723 cites W2112192177 @default.
• W2341236723 cites W2115829042 @default.
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• W2341236723 cites W2116672276 @default.
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• W2341236723 cites W2121673931 @default.
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• W2341236723 cites W2137523780 @default.
• W2341236723 cites W2137988707 @default.
• W2341236723 cites W2142349465 @default.
• W2341236723 cites W2144177541 @default.
• W2341236723 cites W2146580193 @default.
• W2341236723 cites W2148718639 @default.
• W2341236723 cites W2149551170 @default.
• W2341236723 cites W2150770935 @default.
• W2341236723 cites W2151809557 @default.
• W2341236723 cites W2154865244 @default.
• W2341236723 cites W2155563810 @default.
• W2341236723 cites W2156852055 @default.
• W2341236723 cites W2157039533 @default.
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• W2341236723 cites W2165623875 @default.
• W2341236723 cites W2166404610 @default.
• W2341236723 cites W2167654852 @default.
• W2341236723 cites W2169416219 @default.
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• W2341236723 doi "https://doi.org/10.1371/journal.pone.0154279" @default.
• W2341236723 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4839659" @default.
• W2341236723 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27101007" @default.
• W2341236723 hasPublicationYear "2016" @default.
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