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• W2341355847 abstract "Studies have shown that some patients with left-hemispheric brain tumors have an increased propensity for developing right-sided language support. However, the precise trigger for establishing co-dominant language function in brain tumor patients remains unknown. We analyzed the MR scans of patients with left-hemispheric tumors and either co-dominant (n=35) or left-hemisphere dominant (n=35) language function on fMRI to investigate anatomical factors influencing hemispheric language dominance. Of eleven neuroanatomical areas evaluated for tumor involvement, the basal ganglia was significantly correlated with co-dominant language function (p<0.001). Moreover, among patients whose tumors invaded the basal ganglia, those with language co-dominance performed significantly better on the Boston Naming Test, a clinical measure of aphasia, compared to their left-lateralized counterparts (56.5 versus 36.5, p=0.025). While further studies are needed to elucidate the role of the basal ganglia in establishing co-dominance, our results suggest that reactive co-dominance may afford a behavioral advantage to patients with left-hemispheric tumors." @default.
• W2341355847 created "2016-06-24" @default.
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• W2341355847 date "2016-04-01" @default.
• W2341355847 modified "2023-10-16" @default.
• W2341355847 title "Infiltration of the basal ganglia by brain tumors is associated with the development of co-dominant language function on fMRI" @default.
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• W2341355847 doi "https://doi.org/10.1016/j.bandl.2016.04.002" @default.
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