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- W2341451330 abstract "A series of 12 aminophosphonates (AMPP) were synthesized, characterized and tested for their potential biological activity. The antioxidant activity was tested in experimental assays with DPPH• (1,1-diphenyl-2-picryl-hydrazyl) and the potential to function as herbicides, in red blood cells (RBC) membrane destruction experiments. Regarding the reaction with DPPHat least 3 aminophosphonates are better antioxidants than 2,6-di-tert-butyl-4-methylphenol (BHT). Aminophosphonates' capacity to function as herbicide (demonstrated through their hemolytic activity) is given by the presence in their structure of some shorter aliphatic substituents and / or more benzenic nuclei. Rezumat O serie de 12 acizi aminofosfonici si derivaţi (denumiţi generic aminofosfonaţi, AMPP) au fost sintetizaţi, caracterizaţi si testaţi pentru posibila lor activitate biologica. Activitatea antioxidanta a fost testata in determinari experimentale cu DPPH• (1,1-difenil-2-picril-hidrazil) si evaluarea potenţialului de a funcţiona ca erbicide, in experimente de hemoliza a membranei eritrocitare. Activitatea anti- radicalica testata in reacţia cu DPPH•, a dus la concluzia ca cel puţin 3 aminofosfonaţi sunt mai buni antioxidanţi decât 2,6-di-tert-butyl-4-methylphenol (BHT). Probabilitatea de a funcţiona ca erbicid a aminofosfonaţilor (demonstrata prin activitatea hemolitica) este data de existenţa unor substituenţi alifatici de lungime mica si/sau a mai multor nuclee benzenice in structura lor." @default.
- W2341451330 created "2016-06-24" @default.
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- W2341451330 date "2010-01-01" @default.
- W2341451330 modified "2023-09-22" @default.
- W2341451330 title "SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL ACTIVITY OF SOME α-AMINOPHOSPHONATES" @default.
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