FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2341738226> ?p ?o ?g. }

• W2341738226 endingPage "e219" @default.
• W2341738226 startingPage "e206" @default.
• W2341738226 abstract "Immune responses and safety profiles may be affected when vaccines are coadministered. We evaluated the immunogenicity, safety and reactogenicity of a booster dose of the 10-valent pneumococcal nontypeable Haemophilus influenzae protein D-conjugate (PHiD-CV; Synflorix GSK Vaccines) and DTPa-IPV-Hib (Pediacel Sanofi Pasteur MSD) when coadministered.We performed booster assessment in a randomized controlled trial in the Netherlands. Of 780 enrolled healthy infants, 774 toddlers participated in the booster phase and received (1:1:1) (1) PHiD-CV + DTPa-HBV-IPV/Hib (Infanrix hexa, GSK Vaccines), (2) PHiD-CV + DTPa-IPV-Hib, or (3) 7-valent pneumococcal conjugate vaccine (7vCRM, Prevenar/Prevnar, Pfizer, Inc.) + DTPa-IPV-Hib at 2, 3, 4 and 11-13 months old. Blood samples were taken postprimary, prebooster, 1 and 12 months postbooster.Antipneumococcal antibody responses were comparable between both PHiD-CV groups, except for serotype 18C (conjugated to tetanus toxoid). Anti-18C antibody geometric mean concentrations (GMCs) were higher when coadministered with DTPa-HBV-IPV/Hib. For each vaccine serotype, the percentages of children with antibody concentration ≥ 0.20 μg/mL were within the same ranges between PHiD-CV groups (93.8%-100%). The same was observed for the percentages of participants with opsonophagocytic activity titer ≥ 8 (90.9%-100%). When comparing both DTPa-IPV-Hib groups, postbooster antidiphtheria antibody GMCs were higher when coadministered with 7vCRM, while antitetanus and antipolyribosyl-ribitol phosphate antibody GMCs were higher with PHiD-CV coadministration. Regardless, antibody levels to these antigens were well above thresholds. Safety and reactogenicity profiles were comparable between groups.Coadministration of a booster dose of PHiD-CV and DTPa-IPV-Hib was immunogenic and well tolerated." @default.
• W2341738226 created "2016-06-24" @default.
• W2341738226 creator A5044909063 @default.
• W2341738226 creator A5046909895 @default.
• W2341738226 creator A5048500830 @default.
• W2341738226 creator A5049877033 @default.
• W2341738226 creator A5058171363 @default.
• W2341738226 creator A5058621197 @default.
• W2341738226 creator A5068631217 @default.
• W2341738226 creator A5072697665 @default.
• W2341738226 date "2016-07-01" @default.
• W2341738226 modified "2023-10-16" @default.
• W2341738226 title "Immunogenicity, Safety and Reactogenicity of a Booster Dose of the 10-Valent Pneumococcal Nontypeable H. influenzae Protein D Conjugate Vaccine Coadministered With DTPa-IPV-Hib in Dutch Children" @default.
• W2341738226 cites W1976404429 @default.
• W2341738226 cites W1979656937 @default.
• W2341738226 cites W1988038456 @default.
• W2341738226 cites W1990826600 @default.
• W2341738226 cites W2010942366 @default.
• W2341738226 cites W2030178991 @default.
• W2341738226 cites W2038157412 @default.
• W2341738226 cites W2039251425 @default.
• W2341738226 cites W2040607530 @default.
• W2341738226 cites W2044704048 @default.
• W2341738226 cites W2046870614 @default.
• W2341738226 cites W2051453885 @default.
• W2341738226 cites W2054202047 @default.
• W2341738226 cites W2056360579 @default.
• W2341738226 cites W2057943595 @default.
• W2341738226 cites W2058305495 @default.
• W2341738226 cites W2061480752 @default.
• W2341738226 cites W2068751923 @default.
• W2341738226 cites W2074074587 @default.
• W2341738226 cites W2079081917 @default.
• W2341738226 cites W2090499893 @default.
• W2341738226 cites W2092915795 @default.
• W2341738226 cites W2093406963 @default.
• W2341738226 cites W2102997711 @default.
• W2341738226 cites W2113826000 @default.
• W2341738226 cites W2121630139 @default.
• W2341738226 cites W2123962567 @default.
• W2341738226 cites W2127699766 @default.
• W2341738226 cites W2128173146 @default.
• W2341738226 cites W2151165850 @default.
• W2341738226 cites W2151462863 @default.
• W2341738226 cites W2164754521 @default.
• W2341738226 cites W2169803204 @default.
• W2341738226 cites W2177080107 @default.
• W2341738226 cites W2188056236 @default.
• W2341738226 cites W2231979266 @default.
• W2341738226 cites W2312540470 @default.
• W2341738226 cites W4250642730 @default.
• W2341738226 doi "https://doi.org/10.1097/inf.0000000000001170" @default.
• W2341738226 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27097348" @default.
• W2341738226 hasPublicationYear "2016" @default.
• W2341738226 type Work @default.
• W2341738226 sameAs 2341738226 @default.
• W2341738226 citedByCount "11" @default.
• W2341738226 countsByYear W23417382262017 @default.
• W2341738226 countsByYear W23417382262018 @default.
• W2341738226 countsByYear W23417382262019 @default.
• W2341738226 countsByYear W23417382262020 @default.
• W2341738226 countsByYear W23417382262022 @default.
• W2341738226 countsByYear W23417382262023 @default.
• W2341738226 crossrefType "journal-article" @default.
• W2341738226 hasAuthorship W2341738226A5044909063 @default.
• W2341738226 hasAuthorship W2341738226A5046909895 @default.
• W2341738226 hasAuthorship W2341738226A5048500830 @default.
• W2341738226 hasAuthorship W2341738226A5049877033 @default.
• W2341738226 hasAuthorship W2341738226A5058171363 @default.
• W2341738226 hasAuthorship W2341738226A5058621197 @default.
• W2341738226 hasAuthorship W2341738226A5068631217 @default.
• W2341738226 hasAuthorship W2341738226A5072697665 @default.
• W2341738226 hasConcept C12590561 @default.
• W2341738226 hasConcept C159654299 @default.
• W2341738226 hasConcept C203014093 @default.
• W2341738226 hasConcept C2776925733 @default.
• W2341738226 hasConcept C2777704310 @default.
• W2341738226 hasConcept C2778866548 @default.
• W2341738226 hasConcept C2779583294 @default.
• W2341738226 hasConcept C2779592421 @default.
• W2341738226 hasConcept C2780801004 @default.
• W2341738226 hasConcept C2780868878 @default.
• W2341738226 hasConcept C2781253189 @default.
• W2341738226 hasConcept C501593827 @default.
• W2341738226 hasConcept C71924100 @default.
• W2341738226 hasConcept C86803240 @default.
• W2341738226 hasConcept C89423630 @default.
• W2341738226 hasConceptScore W2341738226C12590561 @default.
• W2341738226 hasConceptScore W2341738226C159654299 @default.
• W2341738226 hasConceptScore W2341738226C203014093 @default.
• W2341738226 hasConceptScore W2341738226C2776925733 @default.
• W2341738226 hasConceptScore W2341738226C2777704310 @default.
• W2341738226 hasConceptScore W2341738226C2778866548 @default.
• W2341738226 hasConceptScore W2341738226C2779583294 @default.
• W2341738226 hasConceptScore W2341738226C2779592421 @default.
• W2341738226 hasConceptScore W2341738226C2780801004 @default.
• W2341738226 hasConceptScore W2341738226C2780868878 @default.
• W2341738226 hasConceptScore W2341738226C2781253189 @default.

• next