Matches in SemOpenAlex for { <https://semopenalex.org/work/W2341828181> ?p ?o ?g. }
- W2341828181 endingPage "1111" @default.
- W2341828181 startingPage "1097" @default.
- W2341828181 abstract "The separation of the acetate derivatives of a number of oxygenated sterols was achieved by medium pressure liquid chromatography on silica gel columns and by normal and reversed phase high performance liquid chromatography. We have explored the application of these chromatographic systems for the analysis of oxygenated sterols of plasma samples from two normal human subjects. The addition of highly purified [14C]cholesterol to plasma permitted the detection and quantitation of oxygenated sterols formed by autoxidation of cholesterol during processing of the samples. Special attempts to suppress autoxidation of cholesterol included the use of an all-glass closed system for saponification and extraction under argon followed by rapid removal of cholesterol from the polar sterols by reversed phase medium pressure liquid chromatography. Chromatographic analyses of the [3H]acetate derivatives of the polar sterols provided a sensitive approach for the detection and quantitation of the individual oxygenated sterols. Oxygenated sterols detected in plasma included cholest-5-ene-3 beta,26-diol, (24S)-cholest-5-ene-3 beta,24-diol, and cholest-5-ene-3 beta,7 alpha-diol. After correction for their formation by autoxidation of cholesterol during processing of the samples, very little or none of the following sterols were observed: cholest-5-ene-3 beta,7 beta-diol, 5 alpha,6 alpha-epoxy-cholestan-3 beta-ol, 5 beta,6 beta-epoxy-cholestan-3 beta-ol, and cholestane- 3 beta, 5 alpha,6 beta-triol, and the 25-hydroxy, 22R-hydroxy, 21-hydroxy, 20 alpha-hydroxy, and 19-hydroxy derivatives of cholesterol." @default.
- W2341828181 created "2016-06-24" @default.
- W2341828181 creator A5008831136 @default.
- W2341828181 creator A5041671513 @default.
- W2341828181 creator A5045287676 @default.
- W2341828181 creator A5062314199 @default.
- W2341828181 creator A5062953711 @default.
- W2341828181 creator A5072881070 @default.
- W2341828181 creator A5080354202 @default.
- W2341828181 date "1989-07-01" @default.
- W2341828181 modified "2023-10-16" @default.
- W2341828181 title "Inhibitors of sterol synthesis. Chromatography of acetate derivatives of oxygenated sterols." @default.
- W2341828181 cites W133222152 @default.
- W2341828181 cites W145993992 @default.
- W2341828181 cites W1482506025 @default.
- W2341828181 cites W1497990315 @default.
- W2341828181 cites W1499661648 @default.
- W2341828181 cites W1509346516 @default.
- W2341828181 cites W1513741126 @default.
- W2341828181 cites W1522833156 @default.
- W2341828181 cites W1539699294 @default.
- W2341828181 cites W1541924511 @default.
- W2341828181 cites W1545822782 @default.
- W2341828181 cites W1567633493 @default.
- W2341828181 cites W1583546580 @default.
- W2341828181 cites W1585270155 @default.
- W2341828181 cites W1597768999 @default.
- W2341828181 cites W1607044563 @default.
- W2341828181 cites W1607165966 @default.
- W2341828181 cites W1640148622 @default.
- W2341828181 cites W1926080543 @default.
- W2341828181 cites W1978308663 @default.
- W2341828181 cites W2001452918 @default.
- W2341828181 cites W2002275359 @default.
- W2341828181 cites W2004363335 @default.
- W2341828181 cites W2010064670 @default.
- W2341828181 cites W2024977048 @default.
- W2341828181 cites W2029120060 @default.
- W2341828181 cites W2034644252 @default.
- W2341828181 cites W2040455319 @default.
- W2341828181 cites W2045961447 @default.
- W2341828181 cites W2046925327 @default.
- W2341828181 cites W2047194216 @default.
- W2341828181 cites W2053504146 @default.
- W2341828181 cites W2067391223 @default.
- W2341828181 cites W2068830714 @default.
- W2341828181 cites W2072332057 @default.
- W2341828181 cites W2078406520 @default.
- W2341828181 cites W2084013714 @default.
- W2341828181 cites W2094316417 @default.
- W2341828181 cites W2101690193 @default.
- W2341828181 cites W2151325850 @default.
- W2341828181 cites W2152945072 @default.
- W2341828181 cites W2166738065 @default.
- W2341828181 cites W2182958544 @default.
- W2341828181 cites W2264531640 @default.
- W2341828181 cites W2327104796 @default.
- W2341828181 cites W2342931766 @default.
- W2341828181 cites W2344618307 @default.
- W2341828181 cites W2346010708 @default.
- W2341828181 cites W2346905841 @default.
- W2341828181 cites W2395743264 @default.
- W2341828181 cites W2397797320 @default.
- W2341828181 cites W2409051979 @default.
- W2341828181 cites W2436001985 @default.
- W2341828181 cites W4232293692 @default.
- W2341828181 cites W4232704971 @default.
- W2341828181 cites W4244278739 @default.
- W2341828181 cites W4378945318 @default.
- W2341828181 doi "https://doi.org/10.1016/s0022-2275(20)38296-1" @default.
- W2341828181 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2794792" @default.
- W2341828181 hasPublicationYear "1989" @default.
- W2341828181 type Work @default.
- W2341828181 sameAs 2341828181 @default.
- W2341828181 citedByCount "83" @default.
- W2341828181 countsByYear W23418281812012 @default.
- W2341828181 countsByYear W23418281812013 @default.
- W2341828181 countsByYear W23418281812014 @default.
- W2341828181 countsByYear W23418281812015 @default.
- W2341828181 countsByYear W23418281812016 @default.
- W2341828181 countsByYear W23418281812017 @default.
- W2341828181 countsByYear W23418281812018 @default.
- W2341828181 countsByYear W23418281812020 @default.
- W2341828181 countsByYear W23418281812023 @default.
- W2341828181 crossrefType "journal-article" @default.
- W2341828181 hasAuthorship W2341828181A5008831136 @default.
- W2341828181 hasAuthorship W2341828181A5041671513 @default.
- W2341828181 hasAuthorship W2341828181A5045287676 @default.
- W2341828181 hasAuthorship W2341828181A5062314199 @default.
- W2341828181 hasAuthorship W2341828181A5062953711 @default.
- W2341828181 hasAuthorship W2341828181A5072881070 @default.
- W2341828181 hasAuthorship W2341828181A5080354202 @default.
- W2341828181 hasBestOaLocation W23418281811 @default.
- W2341828181 hasConcept C185592680 @default.
- W2341828181 hasConcept C2778163477 @default.
- W2341828181 hasConcept C2778718757 @default.
- W2341828181 hasConcept C2910061293 @default.
- W2341828181 hasConcept C43617362 @default.