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- W2341904568 abstract "Introduction: Liver transplantation is a well recognized treatment modality for end-stage liver disease. Post operative care requires several steps, including immunosuppression. One of these complications associated with immunosuppression is occurrence of lymphoproliferative disorders, such as lymphoma. This research intended to evaluate the incidence of lymphoma in patients undergoing liver transplantation in a period of 13 years in a university hospital, describe the cases, therapies carried out and outcome. Methods: Data were obtained retrospectively through the analysis of medical records and archives from the liver transplant department. Results: Four cases of lymphoma were found from a series of 685 patients undergoing living transplantation, three were B-cell non-Hodgkin's lymphoma and one, Hodgkin's lymphoma. All patients were submitted to chemotherapy, with the following outcomes: one patient with complete remission four years after diagnosis; one with resistance to treatment and bone marrow transplantation programming; one with treatment interrupted due to toxicity and one who died six months after diagnosis, by meningeal infiltration. Conclusion: Lymphoproliferative disease is a complication associated with liver transplantation and related to immunosuppression. They are cause of morbidity and mortality, but with therapeutic options and good response. It is necessary to follow-up these patients, with investigation and early diagnosis, considering the emergence of cancer as a possible complication in this group." @default.
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- W2341904568 date "2016-04-01" @default.
- W2341904568 modified "2023-10-16" @default.
- W2341904568 title "Lymphoproliferative disorders after liver transplantation, incidence in a period of 13 years in a single institution and a review of literature" @default.
- W2341904568 doi "https://doi.org/10.1016/j.hpb.2016.03.494" @default.
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