Matches in SemOpenAlex for { <https://semopenalex.org/work/W2341909968> ?p ?o ?g. }
- W2341909968 endingPage "1104" @default.
- W2341909968 startingPage "1096" @default.
- W2341909968 abstract "Rationale: Little is known about the effectiveness of noninvasive ventilation for patients hospitalized with asthma exacerbation.Objectives: To assess clinical outcomes of noninvasive (NIV) and invasive mechanical ventilation (IMV) and examine predictors for NIV use in patients hospitalized with asthma.Methods: This was a retrospective cohort study at 97 U.S. hospitals using an electronic medical record database. We developed a hierarchical regression model to identify factors associated with the choice of initial ventilation and used the Laboratory Acute Physiological Score to adjust for differences in the severity of illness. We assessed the outcomes of patients treated with initial NIV or IMV in a propensity-matched cohort.Measurements and Main Results: Among 13,930 subjects, 73% were women and 54% were white. The median age was 53 years. Overall, 1,254 patients (9%) required ventilatory support (NIV or IMV). NIV was the initial ventilation method for 556 patients (4.0%) and IMV for 668 (5.0%). Twenty-six patients (4.7% of patients treated with NIV) had to be intubated (NIV failure). The in-hospital mortality was 0.2, 2.3, 14.5, and 15.4%, and the median length of stay was 2.9, 4.1, 6.7, and 10.9 days among those not ventilated, ventilated with NIV, ventilated with IMV, and with NIV failure, respectively. Older patients were more likely to receive NIV (odds ratio, 1.06 per 5 yr; 95% confidence interval [CI], 1.01–1.11), whereas those with higher acuity (Laboratory Acute Physiological Score per 5 units: odds ratio, 0.85; 95% CI, 0.82–0.88) and those with concomitant pneumonia were less likely to receive NIV. In a propensity-matched sample, NIV was associated with a lower inpatient risk of dying (risk ratio, 0.12; 95% CI, 0.03–0.51) and shorter lengths of stay (4.3 d less; 95% CI, 2.9–5.8) than IMV.Conclusions: Among patients hospitalized with asthma exacerbation and requiring ventilatory support (NIV or IMV), more than 40% received NIV. Although patients successfully treated with NIV appear to have better outcomes than those treated with IMV, the low rate of NIV failure suggests that NIV was being used selectively in a lower risk group. The increased risk of mortality for patients who fail NIV highlights the need for careful monitoring to avoid possible delay in intubation." @default.
- W2341909968 created "2016-06-24" @default.
- W2341909968 creator A5001333980 @default.
- W2341909968 creator A5006559598 @default.
- W2341909968 creator A5016896001 @default.
- W2341909968 creator A5019380630 @default.
- W2341909968 creator A5034425520 @default.
- W2341909968 creator A5038316025 @default.
- W2341909968 creator A5049202803 @default.
- W2341909968 creator A5067286577 @default.
- W2341909968 creator A5067984012 @default.
- W2341909968 creator A5090909661 @default.
- W2341909968 date "2016-07-01" @default.
- W2341909968 modified "2023-10-02" @default.
- W2341909968 title "Outcomes of Noninvasive and Invasive Ventilation in Patients Hospitalized with Asthma Exacerbation" @default.
- W2341909968 cites W1833321994 @default.
- W2341909968 cites W1983373674 @default.
- W2341909968 cites W1984454461 @default.
- W2341909968 cites W2014799253 @default.
- W2341909968 cites W2057780602 @default.
- W2341909968 cites W2079630510 @default.
- W2341909968 cites W2087018232 @default.
- W2341909968 cites W2093484576 @default.
- W2341909968 cites W2095753685 @default.
- W2341909968 cites W2104433800 @default.
- W2341909968 cites W2105093119 @default.
- W2341909968 cites W2110443149 @default.
- W2341909968 cites W2113294453 @default.
- W2341909968 cites W2120234476 @default.
- W2341909968 cites W2124129697 @default.
- W2341909968 cites W2135583319 @default.
- W2341909968 cites W2136203134 @default.
- W2341909968 cites W2136361190 @default.
- W2341909968 cites W2136975742 @default.
- W2341909968 cites W2141692123 @default.
- W2341909968 cites W2145569721 @default.
- W2341909968 cites W2150601163 @default.
- W2341909968 cites W2166150119 @default.
- W2341909968 cites W2211540811 @default.
- W2341909968 cites W2297260804 @default.
- W2341909968 cites W2328661732 @default.
- W2341909968 cites W321076418 @default.
- W2341909968 cites W4240397250 @default.
- W2341909968 cites W4301376207 @default.
- W2341909968 doi "https://doi.org/10.1513/annalsats.201510-701oc" @default.
- W2341909968 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5015747" @default.
- W2341909968 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27070493" @default.
- W2341909968 hasPublicationYear "2016" @default.
- W2341909968 type Work @default.
- W2341909968 sameAs 2341909968 @default.
- W2341909968 citedByCount "35" @default.
- W2341909968 countsByYear W23419099682016 @default.
- W2341909968 countsByYear W23419099682017 @default.
- W2341909968 countsByYear W23419099682018 @default.
- W2341909968 countsByYear W23419099682019 @default.
- W2341909968 countsByYear W23419099682020 @default.
- W2341909968 countsByYear W23419099682021 @default.
- W2341909968 countsByYear W23419099682022 @default.
- W2341909968 countsByYear W23419099682023 @default.
- W2341909968 crossrefType "journal-article" @default.
- W2341909968 hasAuthorship W2341909968A5001333980 @default.
- W2341909968 hasAuthorship W2341909968A5006559598 @default.
- W2341909968 hasAuthorship W2341909968A5016896001 @default.
- W2341909968 hasAuthorship W2341909968A5019380630 @default.
- W2341909968 hasAuthorship W2341909968A5034425520 @default.
- W2341909968 hasAuthorship W2341909968A5038316025 @default.
- W2341909968 hasAuthorship W2341909968A5049202803 @default.
- W2341909968 hasAuthorship W2341909968A5067286577 @default.
- W2341909968 hasAuthorship W2341909968A5067984012 @default.
- W2341909968 hasAuthorship W2341909968A5090909661 @default.
- W2341909968 hasBestOaLocation W23419099682 @default.
- W2341909968 hasConcept C126322002 @default.
- W2341909968 hasConcept C127413603 @default.
- W2341909968 hasConcept C156957248 @default.
- W2341909968 hasConcept C167135981 @default.
- W2341909968 hasConcept C194828623 @default.
- W2341909968 hasConcept C195910791 @default.
- W2341909968 hasConcept C200457457 @default.
- W2341909968 hasConcept C2776042228 @default.
- W2341909968 hasConcept C2777014857 @default.
- W2341909968 hasConcept C2777080012 @default.
- W2341909968 hasConcept C3019440749 @default.
- W2341909968 hasConcept C44249647 @default.
- W2341909968 hasConcept C71924100 @default.
- W2341909968 hasConcept C72563966 @default.
- W2341909968 hasConcept C78519656 @default.
- W2341909968 hasConceptScore W2341909968C126322002 @default.
- W2341909968 hasConceptScore W2341909968C127413603 @default.
- W2341909968 hasConceptScore W2341909968C156957248 @default.
- W2341909968 hasConceptScore W2341909968C167135981 @default.
- W2341909968 hasConceptScore W2341909968C194828623 @default.
- W2341909968 hasConceptScore W2341909968C195910791 @default.
- W2341909968 hasConceptScore W2341909968C200457457 @default.
- W2341909968 hasConceptScore W2341909968C2776042228 @default.
- W2341909968 hasConceptScore W2341909968C2777014857 @default.
- W2341909968 hasConceptScore W2341909968C2777080012 @default.
- W2341909968 hasConceptScore W2341909968C3019440749 @default.
- W2341909968 hasConceptScore W2341909968C44249647 @default.