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- W2342114719 abstract "Background/Aims: Terlipressin decreases portal pressure. However, its effects on variceal pressure have been poorly investigated. This study investigated the variceal, splanchnic and systemic hemodynamic effects of terlipressin. Methods: ‘Itventy cirrhotic patients with esophageal varices grade II-III, and portal pressure 212 mmHg were studied. Hepatic venous pressure gradient, variceal pressure and systemic hemodynamic parameters were obtained. After baseline measurements, in a double-blind administration, 14 patients received a 2mg/iv injection of terlipressin and six patients received placebo. The same measurements were repeated 60 min later. Results: No demographic or biochemical differences were observed in basal condition between groups. Terlipressin produced significant decreases in intravariceal pressure from 20.9k4.9 to 16.324.7 mmHg (pCO.01, -21&16%), variceal pressure gradient from 18.924.8 to 13526.0 mmHg QKO.01, -28*27%), estimated variceal wall tension from 78229 to 59231 ARICEAL BLEEDING is a frequent and severe compli" @default.
- W2342114719 created "2016-06-24" @default.
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- W2342114719 date "2000-01-01" @default.
- W2342114719 modified "2023-09-27" @default.
- W2342114719 title "Terlipressin is more effective in decreasing vat&al pressure in cirrhotic patients pressure than portal" @default.
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