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- W2342304889 endingPage "863" @default.
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- W2342304889 abstract "The intestinal epithelium is the main barrier restricting the oral delivery of low-permeability drugs. Over recent years, numerous nanocarriers have been designed to improve the efficiency of oral drug delivery. However, the intracellular processes determining the transport of nanocarriers across the intestinal epithelium remain elusive, and only limited enhancement of the oral bioavailability of drugs has been achieved. Here, we review the processes involved in nanocarrier trafficking across the intestinal epithelium, including apical endocytosis, intracellular transport, and basolateral exocytosis. Understanding the complex intracellular processes of nanocarrier trafficking is particularly essential for the rational design of oral drug delivery systems." @default.
- W2342304889 created "2016-06-24" @default.
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- W2342304889 date "2016-05-01" @default.
- W2342304889 modified "2023-10-14" @default.
- W2342304889 title "Intracellular transport of nanocarriers across the intestinal epithelium" @default.
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- W2342304889 doi "https://doi.org/10.1016/j.drudis.2016.04.007" @default.
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