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• W2342374783 abstract "Perioperative hypovolemia and fluid overload have effects on both complications following surgery and on patient survival. Therefore, the administration of intravenous fluids before, during, and after surgery at the right time and in the right amounts is of great importance. This review aims to analyze the literature concerning perioperative fluid therapy in abdominal surgery and to provide evidence-based recommendations for clinical practice.Preoperative oral or intravenous administration of carbohydrate containing fluids has been shown to improve postoperative well-being and muscular strength and to reduce insulin resistance. Hence, the intake of fluid (preferably containing carbohydrates) should be encouraged up to 2 h prior to surgery in order to avoid dehydration. Excessive intravenous fluid administration adds to tissue inflammation and edema formation, thereby compromising tissue healing. During major abdominal surgery a zero-balance intraoperative fluid strategy aims at avoiding fluid overload (and comparable to the so-called restrictive approach) as well as goal-directed fluid therapy (GDT). Both proved to significantly reduce postoperative complications when compared to standard fluid therapy. Trials comparing restrictive or zero-balance and GDT have shown equal results, as long as fluid overload is avoided in the GDT group as well (categorized as zero-balance GDT). It is possible that high-risk surgical patients, such as those undergoing acute surgery, may benefit from the continuous monitoring of circulatory status that the GDT provides. Data on this group of patients is not available at present, but trials are ongoing.In elective surgery, the zero-balance approach has shown to reduce postoperative complications and is easily applied for most patients. It is less expensive and simpler than the zero-balance GDT approach and therefore recommended in this review. In outpatient surgery, 1-2 L of balanced crystalloids reduces postoperative nausea and vomiting and improves well-being." @default.
• W2342374783 created "2016-06-24" @default.
• W2342374783 creator A5056110861 @default.
• W2342374783 creator A5077532230 @default.
• W2342374783 date "2016-04-16" @default.
• W2342374783 modified "2023-10-13" @default.
• W2342374783 title "Fluid therapy in the perioperative setting—a clinical review" @default.
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• W2342374783 doi "https://doi.org/10.1186/s40560-016-0154-3" @default.
• W2342374783 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4833950" @default.
• W2342374783 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27087980" @default.
• W2342374783 hasPublicationYear "2016" @default.
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