Matches in SemOpenAlex for { <https://semopenalex.org/work/W2342893392> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W2342893392 abstract "The present investigation concerns with the development and evaluation of the floating matrix tablets of Salbutmol Sulphate. Tablets were prepared by wet granulation method. Â Hydroxypropyl methylcellulose and ethyl cellulose was used as a release retardant material. Sodium bicarbonate and Citric acid was incorporated as a gas-generating agent. The effects of Sodium bicarbonate and citric acid on drug release profile, floating properties and matrix integrity of tablet were investigated. Addition of Citric acid in excess amount results in disintegration of the tablet so the floating tablets are prepared by full 32 factorial designs by reducing the ratio of citric acid. Developed formulations were evaluated for their physical characteristics, drug content, floating lag time, floating duration, in vitro drug release profile etc. On the basis of various physical characteristics parameters it was found that all the formulations shows good result. On comparative kinetic modeling study such as (Zero order, Higuchi model and Korsmeyer-Peppas) it was found that all the formulations follow Higuchi model and correlation coefficient (R2) and Korsmeyer model values were nearer to unity. Among those formulations F8 and F9 showed R2 value of Higuchi model more near as compared to the other formulation. KEYWORDS: Salbutmol sulphate, Ethyl cellulose, HPMC, Sodium bicarbonate, Citric acid, Tartaric acid." @default.
- W2342893392 created "2016-06-24" @default.
- W2342893392 creator A5004647875 @default.
- W2342893392 creator A5022457042 @default.
- W2342893392 date "2013-05-15" @default.
- W2342893392 modified "2023-09-26" @default.
- W2342893392 title "MODULATION OF GASTROINTESTINAL TRANSIT TIME OF SALBUTAAMOL SULPHATE BY FLOATING APPROCHES" @default.
- W2342893392 doi "https://doi.org/10.22270/jddt.v3i3.502" @default.
- W2342893392 hasPublicationYear "2013" @default.
- W2342893392 type Work @default.
- W2342893392 sameAs 2342893392 @default.
- W2342893392 citedByCount "0" @default.
- W2342893392 crossrefType "journal-article" @default.
- W2342893392 hasAuthorship W2342893392A5004647875 @default.
- W2342893392 hasAuthorship W2342893392A5022457042 @default.
- W2342893392 hasBestOaLocation W23428933921 @default.
- W2342893392 hasConcept C105795698 @default.
- W2342893392 hasConcept C106487976 @default.
- W2342893392 hasConcept C159985019 @default.
- W2342893392 hasConcept C169222746 @default.
- W2342893392 hasConcept C178790620 @default.
- W2342893392 hasConcept C185592680 @default.
- W2342893392 hasConcept C192562407 @default.
- W2342893392 hasConcept C205474432 @default.
- W2342893392 hasConcept C2776035855 @default.
- W2342893392 hasConcept C2776420369 @default.
- W2342893392 hasConcept C2779032678 @default.
- W2342893392 hasConcept C2780048820 @default.
- W2342893392 hasConcept C33923547 @default.
- W2342893392 hasConcept C43617362 @default.
- W2342893392 hasConcept C521977710 @default.
- W2342893392 hasConcept C88463166 @default.
- W2342893392 hasConceptScore W2342893392C105795698 @default.
- W2342893392 hasConceptScore W2342893392C106487976 @default.
- W2342893392 hasConceptScore W2342893392C159985019 @default.
- W2342893392 hasConceptScore W2342893392C169222746 @default.
- W2342893392 hasConceptScore W2342893392C178790620 @default.
- W2342893392 hasConceptScore W2342893392C185592680 @default.
- W2342893392 hasConceptScore W2342893392C192562407 @default.
- W2342893392 hasConceptScore W2342893392C205474432 @default.
- W2342893392 hasConceptScore W2342893392C2776035855 @default.
- W2342893392 hasConceptScore W2342893392C2776420369 @default.
- W2342893392 hasConceptScore W2342893392C2779032678 @default.
- W2342893392 hasConceptScore W2342893392C2780048820 @default.
- W2342893392 hasConceptScore W2342893392C33923547 @default.
- W2342893392 hasConceptScore W2342893392C43617362 @default.
- W2342893392 hasConceptScore W2342893392C521977710 @default.
- W2342893392 hasConceptScore W2342893392C88463166 @default.
- W2342893392 hasLocation W23428933921 @default.
- W2342893392 hasOpenAccess W2342893392 @default.
- W2342893392 hasPrimaryLocation W23428933921 @default.
- W2342893392 hasRelatedWork W1512408772 @default.
- W2342893392 hasRelatedWork W2076684536 @default.
- W2342893392 hasRelatedWork W2102206924 @default.
- W2342893392 hasRelatedWork W2335744757 @default.
- W2342893392 hasRelatedWork W2414029243 @default.
- W2342893392 hasRelatedWork W2439720966 @default.
- W2342893392 hasRelatedWork W2890770295 @default.
- W2342893392 hasRelatedWork W2920628423 @default.
- W2342893392 hasRelatedWork W2997611768 @default.
- W2342893392 hasRelatedWork W3163185935 @default.
- W2342893392 hasRelatedWork W2182557472 @default.
- W2342893392 hasRelatedWork W2186348221 @default.
- W2342893392 hasRelatedWork W2187284964 @default.
- W2342893392 hasRelatedWork W2188155462 @default.
- W2342893392 hasRelatedWork W2188221718 @default.
- W2342893392 hasRelatedWork W2188429691 @default.
- W2342893392 hasRelatedWork W2495480397 @default.
- W2342893392 hasRelatedWork W2559910907 @default.
- W2342893392 hasRelatedWork W2563262581 @default.
- W2342893392 hasRelatedWork W3146016168 @default.
- W2342893392 isParatext "false" @default.
- W2342893392 isRetracted "false" @default.
- W2342893392 magId "2342893392" @default.
- W2342893392 workType "article" @default.