Matches in SemOpenAlex for { <https://semopenalex.org/work/W2343293104> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2343293104 abstract "The objectives of this study were to assess the prevalence of cartilage erosion in small dogs with patellar luxation (PL), and related osteoarthritis (OA)-related gene expression. In Study 1, 71 dogs were examined to determine risk factors associated with PL, including breed, age, weight, sex, and affected joint. In Study 2, a total of 39 dogs were divided into four groups: normal articular cartilage in the stifle joint (G1; n=5); PL without cartilage erosion (G2; n=11); PL with cartilage erosion (G3; n=14); and OA in the stifle (G4; n=9). Articular cartilage and synovial membranes were collected during surgical operations to correct PL. Real-time PCR was used to quantify the expression levels of 11 OA-related genes, including AGG, COL2A1, HAS-1, HAS-2, TIMP-1, MMP-3, IL-1β, TNF-α, IFN-γ, COX-1, and COX-2, with GAPDH used as a reference gene. From Study 1, it was found that the risk factors related with cartilage erosion lesion were age, sex, and PL grade (all variables showed P<0.05). From Study 2, it was demonstrated that PL with or without cartilage erosion expressed pro-inflammatory cytokines and enzymes; some biomolecules were up regulated (IL-1β, MMP-3, AGG, TIMP-1) but some were down regulated (COL2A1, HAS-2, COX-1, COX-2). This expression was the difference between the articular cartilage and the synovial membrane; however, the expression of genes from PL with cartilage erosion was observed to be similar to that of OA. From our results, it can be concluded that PL can develop into secondary OA due to an increase of IL-1β in cartilage and synovial membrane." @default.
- W2343293104 created "2016-06-24" @default.
- W2343293104 creator A5008406901 @default.
- W2343293104 creator A5009455195 @default.
- W2343293104 creator A5012294040 @default.
- W2343293104 creator A5015945178 @default.
- W2343293104 creator A5021829119 @default.
- W2343293104 creator A5072781321 @default.
- W2343293104 creator A5082797791 @default.
- W2343293104 date "2016-01-01" @default.
- W2343293104 modified "2023-10-18" @default.
- W2343293104 title "Köpeklerde Patellar Luksasyonda Kıkırdak Erozyonunun Prevalansı ve Etkilenmiş Eklemlerdeki Gen Ekspresyonu" @default.
- W2343293104 cites W144491073 @default.
- W2343293104 cites W1513925829 @default.
- W2343293104 cites W1528476591 @default.
- W2343293104 cites W1773041043 @default.
- W2343293104 cites W1913198287 @default.
- W2343293104 cites W1933832490 @default.
- W2343293104 cites W1964591612 @default.
- W2343293104 cites W1968901258 @default.
- W2343293104 cites W1975656293 @default.
- W2343293104 cites W1982353151 @default.
- W2343293104 cites W1998973775 @default.
- W2343293104 cites W2002436660 @default.
- W2343293104 cites W2004806078 @default.
- W2343293104 cites W2025598635 @default.
- W2343293104 cites W2027164465 @default.
- W2343293104 cites W2027251634 @default.
- W2343293104 cites W2028760985 @default.
- W2343293104 cites W2038696970 @default.
- W2343293104 cites W2039563644 @default.
- W2343293104 cites W2039680442 @default.
- W2343293104 cites W2045891164 @default.
- W2343293104 cites W2060991519 @default.
- W2343293104 cites W2064674162 @default.
- W2343293104 cites W2072317825 @default.
- W2343293104 cites W2075536483 @default.
- W2343293104 cites W2097178712 @default.
- W2343293104 cites W2097605691 @default.
- W2343293104 cites W2100052794 @default.
- W2343293104 cites W2108692325 @default.
- W2343293104 cites W2112280420 @default.
- W2343293104 cites W2113778227 @default.
- W2343293104 cites W2116044476 @default.
- W2343293104 cites W2126313701 @default.
- W2343293104 cites W2133000252 @default.
- W2343293104 cites W2137486822 @default.
- W2343293104 cites W2141859090 @default.
- W2343293104 cites W2148094785 @default.
- W2343293104 cites W2162151580 @default.
- W2343293104 cites W2164531777 @default.
- W2343293104 cites W2168016554 @default.
- W2343293104 doi "https://doi.org/10.9775/kvfd.2016.15036" @default.
- W2343293104 hasPublicationYear "2016" @default.
- W2343293104 type Work @default.
- W2343293104 sameAs 2343293104 @default.
- W2343293104 citedByCount "0" @default.
- W2343293104 crossrefType "journal-article" @default.
- W2343293104 hasAuthorship W2343293104A5008406901 @default.
- W2343293104 hasAuthorship W2343293104A5009455195 @default.
- W2343293104 hasAuthorship W2343293104A5012294040 @default.
- W2343293104 hasAuthorship W2343293104A5015945178 @default.
- W2343293104 hasAuthorship W2343293104A5021829119 @default.
- W2343293104 hasAuthorship W2343293104A5072781321 @default.
- W2343293104 hasAuthorship W2343293104A5082797791 @default.
- W2343293104 hasBestOaLocation W23432931041 @default.
- W2343293104 hasConcept C118121272 @default.
- W2343293104 hasConcept C121332964 @default.
- W2343293104 hasConcept C1276947 @default.
- W2343293104 hasConceptScore W2343293104C118121272 @default.
- W2343293104 hasConceptScore W2343293104C121332964 @default.
- W2343293104 hasConceptScore W2343293104C1276947 @default.
- W2343293104 hasLocation W23432931041 @default.
- W2343293104 hasOpenAccess W2343293104 @default.
- W2343293104 hasPrimaryLocation W23432931041 @default.
- W2343293104 hasRelatedWork W2130800705 @default.
- W2343293104 hasRelatedWork W2132359678 @default.
- W2343293104 hasRelatedWork W2566176698 @default.
- W2343293104 hasRelatedWork W2592583281 @default.
- W2343293104 hasRelatedWork W2901773020 @default.
- W2343293104 hasRelatedWork W3098522415 @default.
- W2343293104 hasRelatedWork W3121119400 @default.
- W2343293104 hasRelatedWork W3155118157 @default.
- W2343293104 hasRelatedWork W4242234006 @default.
- W2343293104 hasRelatedWork W4319342112 @default.
- W2343293104 isParatext "false" @default.
- W2343293104 isRetracted "false" @default.
- W2343293104 magId "2343293104" @default.
- W2343293104 workType "article" @default.