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• W2343921951 abstract "The photothermal optical lock-in optical coherence microscope (poli-OCM) introduced molecular specificity to OCM imaging, which is conventionally, a label-free technique. Here we achieve three-dimensional live cell and mitochondria specific imaging using ~4nm protein-functionalized gold nanoparticles (AuNPs). These nanoparticles do not photobleach and we demonstrate they’re suitability for long-term time lapse imaging. We compare the accuracy of labelling with these AuNPs using classical fluorescence confocal imaging with a standard mitochondria specific marker. Furthermore, time lapse poli-OCM imaging every 5 minutes over 1.5 hours period was achieved, revealing the ability for three-dimensional monitoring of mitochondria dynamics." @default.
• W2343921951 created "2016-06-24" @default.
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• W2343921951 date "2016-04-26" @default.
• W2343921951 modified "2023-10-10" @default.
• W2343921951 title "Three dimensional time lapse imaging of live cell mitochondria with photothermal optical lock-in optical coherence microscopy (Conference Presentation)" @default.
• W2343921951 doi "https://doi.org/10.1117/12.2214761" @default.
• W2343921951 hasPublicationYear "2016" @default.
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