Matches in SemOpenAlex for { <https://semopenalex.org/work/W2344088863> ?p ?o ?g. }
- W2344088863 endingPage "2188" @default.
- W2344088863 startingPage "2178" @default.
- W2344088863 abstract "Acellular hydroxyapatite (HA) reinforced collagen scaffolds were previously reported to induce angiogenesis and osteogenesis after ectopic implantation but the effect of the HA volume fraction was not investigated. Therefore, the objective of this study was to investigate the effect of HA volume fraction on in vivo angiogenesis and osteogenesis in acellular collagen scaffolds containing 0, 20, and 40 vol % HA after subcutaneous ectopic implantation for up to 12 weeks in mice. Endogenous cell populations were able to completely and uniformly infiltrate the entire scaffold within 6 weeks independent of the HA content, but the cell density was increased in scaffolds containing HA versus collagen alone. Angiogenesis, remodeling of the original scaffold matrix, mineralization, and osteogenic gene expression were evident in scaffolds containing HA, but were not observed in collagen scaffolds. Moreover, HA promoted a dose-dependent increase in measured vascular density, cell density, matrix deposition, and mineralization. Therefore, the results of this study suggest that HA promoted the recruitment and differentiation of endogenous cell populations to support angiogenic and osteogenic activity in collagen scaffolds after subcutaneous ectopic implantation. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 104A: 2178–2188, 2016." @default.
- W2344088863 created "2016-06-24" @default.
- W2344088863 creator A5026966989 @default.
- W2344088863 creator A5027057356 @default.
- W2344088863 creator A5032144064 @default.
- W2344088863 creator A5055411404 @default.
- W2344088863 creator A5057141572 @default.
- W2344088863 creator A5091721315 @default.
- W2344088863 date "2016-05-03" @default.
- W2344088863 modified "2023-09-26" @default.
- W2344088863 title "Acellular hydroxyapatite‐collagen scaffolds support angiogenesis and osteogenic gene expression in an ectopic murine model: Effects of hydroxyapatite volume fraction" @default.
- W2344088863 cites W1975280273 @default.
- W2344088863 cites W1977175847 @default.
- W2344088863 cites W1977273370 @default.
- W2344088863 cites W1979511685 @default.
- W2344088863 cites W1982033742 @default.
- W2344088863 cites W1982685685 @default.
- W2344088863 cites W1988785917 @default.
- W2344088863 cites W1990910070 @default.
- W2344088863 cites W1991956475 @default.
- W2344088863 cites W1997604272 @default.
- W2344088863 cites W1997697459 @default.
- W2344088863 cites W1999959517 @default.
- W2344088863 cites W2003852585 @default.
- W2344088863 cites W2006801551 @default.
- W2344088863 cites W2007990569 @default.
- W2344088863 cites W2013318838 @default.
- W2344088863 cites W2016982708 @default.
- W2344088863 cites W2020778747 @default.
- W2344088863 cites W2022213375 @default.
- W2344088863 cites W2025422403 @default.
- W2344088863 cites W2026104001 @default.
- W2344088863 cites W2026518450 @default.
- W2344088863 cites W2030629852 @default.
- W2344088863 cites W2036177694 @default.
- W2344088863 cites W2047422913 @default.
- W2344088863 cites W2050061366 @default.
- W2344088863 cites W2051746941 @default.
- W2344088863 cites W2054212795 @default.
- W2344088863 cites W2058352669 @default.
- W2344088863 cites W2058833447 @default.
- W2344088863 cites W2059779956 @default.
- W2344088863 cites W2064254408 @default.
- W2344088863 cites W2064726462 @default.
- W2344088863 cites W2065125081 @default.
- W2344088863 cites W2067380741 @default.
- W2344088863 cites W2070199257 @default.
- W2344088863 cites W2071612886 @default.
- W2344088863 cites W2084469238 @default.
- W2344088863 cites W2087878184 @default.
- W2344088863 cites W2101601223 @default.
- W2344088863 cites W2101682146 @default.
- W2344088863 cites W2102618636 @default.
- W2344088863 cites W2103492381 @default.
- W2344088863 cites W2115327066 @default.
- W2344088863 cites W2116741306 @default.
- W2344088863 cites W2118501085 @default.
- W2344088863 cites W2119583980 @default.
- W2344088863 cites W2128128715 @default.
- W2344088863 cites W2134208433 @default.
- W2344088863 cites W2139202419 @default.
- W2344088863 cites W2139457077 @default.
- W2344088863 cites W2139586508 @default.
- W2344088863 cites W2143228190 @default.
- W2344088863 cites W2143576830 @default.
- W2344088863 cites W2167346909 @default.
- W2344088863 cites W2199338994 @default.
- W2344088863 cites W72508250 @default.
- W2344088863 doi "https://doi.org/10.1002/jbm.a.35760" @default.
- W2344088863 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27112109" @default.
- W2344088863 hasPublicationYear "2016" @default.
- W2344088863 type Work @default.
- W2344088863 sameAs 2344088863 @default.
- W2344088863 citedByCount "37" @default.
- W2344088863 countsByYear W23440888632016 @default.
- W2344088863 countsByYear W23440888632017 @default.
- W2344088863 countsByYear W23440888632018 @default.
- W2344088863 countsByYear W23440888632019 @default.
- W2344088863 countsByYear W23440888632020 @default.
- W2344088863 countsByYear W23440888632021 @default.
- W2344088863 countsByYear W23440888632022 @default.
- W2344088863 countsByYear W23440888632023 @default.
- W2344088863 crossrefType "journal-article" @default.
- W2344088863 hasAuthorship W2344088863A5026966989 @default.
- W2344088863 hasAuthorship W2344088863A5027057356 @default.
- W2344088863 hasAuthorship W2344088863A5032144064 @default.
- W2344088863 hasAuthorship W2344088863A5055411404 @default.
- W2344088863 hasAuthorship W2344088863A5057141572 @default.
- W2344088863 hasAuthorship W2344088863A5091721315 @default.
- W2344088863 hasConcept C106487976 @default.
- W2344088863 hasConcept C136229726 @default.
- W2344088863 hasConcept C150903083 @default.
- W2344088863 hasConcept C159985019 @default.
- W2344088863 hasConcept C192562407 @default.
- W2344088863 hasConcept C207001950 @default.
- W2344088863 hasConcept C2780394083 @default.
- W2344088863 hasConcept C502942594 @default.
- W2344088863 hasConcept C71924100 @default.