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- W2344300812 abstract "We evaluated the effects of avanafil on semen quality in oligoasthenospermic infertile (OAI) men. The present study was initially scheduled to include 39 OAI-men. When each patient was recruited they were randomly assigned to one of three groups A, B, and C. In all, 13 OAI-men were treated daily for 12 weeks with avanafil (50 mg three times a day; group A), or L-carnitine (14 men; positive control group; 1.5 g per day group B); another group of 12 OAI-men (group C; negative control group) received no treatment. Semen parameters, the mean length of sperm midpiece (LMP), the outcome of hypoosmotic swelling test (%HPST), and the seminal plasma citrate concentration (secreted by the prostate) were evaluated before and after the end of the treatment in each of groups A and B and before and at the end of the 12-week-experimental period (EP) in group C, respectively. Serum levels of testosterone were evaluated before and at the end of the EP in each of groups A, B, or C. Wilcoxon paired test was used for statistical analysis. A probability P smaller than 0.05 was considered as significant." @default.
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- W2344300812 date "2016-05-01" @default.
- W2344300812 modified "2023-10-16" @default.
- W2344300812 title "P-01-065 Effects of Avanafil on Semen Quality and Sperm Cytoskeleton in Oligoasthenospermic Infertile Men: A Randomized Controlled Trial" @default.
- W2344300812 doi "https://doi.org/10.1016/j.jsxm.2016.03.216" @default.
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