Matches in SemOpenAlex for { <https://semopenalex.org/work/W2344707987> ?p ?o ?g. }
- W2344707987 endingPage "289" @default.
- W2344707987 startingPage "261" @default.
- W2344707987 abstract "Biomolecule-sensitive hydrogels that undergo volumetric changes in response to a target biomolecule such as glucose and proteins have become increasingly important because of their potential applications as smart biomaterials for constructing self-regulated drug-delivery systems (DDSs) and diagnostic systems. However, there have not been so many studies on biomolecule-sensitive hydrogels, due to difficulties in combining biomolecular recognition abilities with responsive functions within a hydrogel. This chapter introduces some strategies for designing biomolecule-sensitive hydrogels that exhibit swelling/shrinking behavior or sol-gel transition in response to the concentration of a target biomolecule. A standard strategy is to combine the molecular recognition events of biomolecules such as enzymes, lectins and antibodies with responsiveness of pH- and temperature-sensitive polymers. Another strategy uses biomolecular complexes like those of lectin-saccharide and antigen-antibody as dynamic cross-links of hydrogel networks. Designs of biomolecule-sensitive hydrogels will contribute significantly to develop smart DDSs in which specific amounts of drugs can be administered with monitoring specific biomolecules as diagnostic signals for several physiological changes. This chapter provides an overview of important researches about biomolecule-sensitive hydrogels for DDSs and diagnosis, focusing on saccharides, proteins, DNAs, etc. as target biomolecules." @default.
- W2344707987 created "2016-06-24" @default.
- W2344707987 creator A5039946998 @default.
- W2344707987 date "2013-04-17" @default.
- W2344707987 modified "2023-09-30" @default.
- W2344707987 title "Biomolecule-sensitive Hydrogels" @default.
- W2344707987 cites W1515338173 @default.
- W2344707987 cites W1541586103 @default.
- W2344707987 cites W155156277 @default.
- W2344707987 cites W1631248633 @default.
- W2344707987 cites W1881070081 @default.
- W2344707987 cites W1966438319 @default.
- W2344707987 cites W1967365802 @default.
- W2344707987 cites W1968251043 @default.
- W2344707987 cites W1968844151 @default.
- W2344707987 cites W1970751992 @default.
- W2344707987 cites W1973992905 @default.
- W2344707987 cites W1974054296 @default.
- W2344707987 cites W1975997188 @default.
- W2344707987 cites W1976984523 @default.
- W2344707987 cites W1978909966 @default.
- W2344707987 cites W1982083799 @default.
- W2344707987 cites W1984240603 @default.
- W2344707987 cites W1984380683 @default.
- W2344707987 cites W1989947315 @default.
- W2344707987 cites W1996026948 @default.
- W2344707987 cites W1996173073 @default.
- W2344707987 cites W1996206820 @default.
- W2344707987 cites W1996803782 @default.
- W2344707987 cites W1997789388 @default.
- W2344707987 cites W1998531886 @default.
- W2344707987 cites W2000405623 @default.
- W2344707987 cites W2001046276 @default.
- W2344707987 cites W2001280311 @default.
- W2344707987 cites W2004976115 @default.
- W2344707987 cites W2005924974 @default.
- W2344707987 cites W2006705312 @default.
- W2344707987 cites W2007575820 @default.
- W2344707987 cites W2010478256 @default.
- W2344707987 cites W2013512466 @default.
- W2344707987 cites W2015845303 @default.
- W2344707987 cites W2017394173 @default.
- W2344707987 cites W2018818236 @default.
- W2344707987 cites W2027742586 @default.
- W2344707987 cites W2029775351 @default.
- W2344707987 cites W2033696759 @default.
- W2344707987 cites W2034628650 @default.
- W2344707987 cites W2034671557 @default.
- W2344707987 cites W2036519445 @default.
- W2344707987 cites W2037621579 @default.
- W2344707987 cites W2038615507 @default.
- W2344707987 cites W2040011847 @default.
- W2344707987 cites W2040189760 @default.
- W2344707987 cites W2043325430 @default.
- W2344707987 cites W2044390916 @default.
- W2344707987 cites W2046298784 @default.
- W2344707987 cites W2046838788 @default.
- W2344707987 cites W2047789450 @default.
- W2344707987 cites W2051086698 @default.
- W2344707987 cites W2053590226 @default.
- W2344707987 cites W2054016004 @default.
- W2344707987 cites W2054531210 @default.
- W2344707987 cites W2057586855 @default.
- W2344707987 cites W2061799155 @default.
- W2344707987 cites W2064966634 @default.
- W2344707987 cites W2065315696 @default.
- W2344707987 cites W2065342469 @default.
- W2344707987 cites W2067928133 @default.
- W2344707987 cites W2074399846 @default.
- W2344707987 cites W2074581132 @default.
- W2344707987 cites W2076703860 @default.
- W2344707987 cites W2079279347 @default.
- W2344707987 cites W2080806331 @default.
- W2344707987 cites W2084064316 @default.
- W2344707987 cites W2086610977 @default.
- W2344707987 cites W2087028929 @default.
- W2344707987 cites W2087208805 @default.
- W2344707987 cites W2091288913 @default.
- W2344707987 cites W2092222250 @default.
- W2344707987 cites W2100501295 @default.
- W2344707987 cites W2103571372 @default.
- W2344707987 cites W2104413873 @default.
- W2344707987 cites W2109782053 @default.
- W2344707987 cites W2121775179 @default.
- W2344707987 cites W2122086796 @default.
- W2344707987 cites W2124599841 @default.
- W2344707987 cites W2132243232 @default.
- W2344707987 cites W2133557431 @default.
- W2344707987 cites W2137690919 @default.
- W2344707987 cites W2139347733 @default.
- W2344707987 cites W2142962347 @default.
- W2344707987 cites W2148845788 @default.
- W2344707987 cites W2152874444 @default.
- W2344707987 cites W2156224745 @default.
- W2344707987 cites W2157534494 @default.
- W2344707987 cites W2160061574 @default.
- W2344707987 cites W2161853058 @default.
- W2344707987 cites W2235334685 @default.