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- W2344758437 abstract "The hepa s C virus (HCV) was iden fi ed in 1989, and it is a major public health problem and a leading cause of chronic liver disease.1 All over the world, hepa s C is the principle cause of death from liver disease and the leading indica on for liver transplanta on.2 The prevalence of HCV globally is 3% and approximately 170 million people are infected. The spectrum of liver disease caused by it includes acute hepa s (although rare), chronic hepa s, liver failure, cirrhosis and hepatocellular carcinoma (HCC). In majority of pa ents acute HCV infec on is asymptoma c. In almost all the pa ents, within 1–2 weeks of exposure the HCV-RNA can be detected in the serum, while an -HCV may take 4–6 weeks. The fi rst 6 months is usually considered as an acute phase of infec on and during this phase spontaneous clearance is s ll a possibility. Approximately 50–80% of the pa ents of acute hepa s develop chronic infec on, while 20–50% of pa ents achieve spontaneous resolu on. Among pa ents with chronic hepa c C, approximately 20% can be expected to develop cirrhosis; of these, 6% of the pa ents will decompensate to end-stage liver disease (ESLD) and an addi onal 4% will develop HCC. Chronic hepa s C is a chronic viral infec on that can be cured by an viral therapy.2" @default.
- W2344758437 created "2016-06-24" @default.
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- W2344758437 date "2013-01-01" @default.
- W2344758437 modified "2023-09-23" @default.
- W2344758437 title "Management of Hepatitis C" @default.
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