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- W2344897488 abstract "En el contexto de un proceso infeccioso sistémico, es frecuente la presencia de alteraciones clínicas o analíticas que sugieren afectación a nivel hepático. Estas alteraciones, sin embargo, no siempre se justifican por una colonización directa del agente infeccioso en el parénquima hepático o biliar, sino que también pueden tener un origen indirecto a través del daño mediado por endotoxinemia o bacteriemia, o bien isquémico, en el contexto de una sepsis grave. La etiología de la enfermedad hepática de origen infeccioso es variable e incluye bacterias, virus, hongos y parásitos. La frecuencia con la que se presentan cada una de ellas varía fundamentalmente en función del espacio geográfico en el que nos encontremos y del estado de inmunocompetencia del paciente. En esta revisión, se abordarán las manifestaciones hepáticas en infecciones bacterianas, fúngicas y por parásitos, así como las principales infecciones oportunistas en el enfermo por el VIH. It is frequent to observe an abnormal liver function test or liver related symptoms in the course of systemic infections. Nevertheless, these conditions do not always mirror a direct liver colonization and can be due to indirect liver damage mediated by endotoxemia and bacteriemia as well as an ischemic injury in the context of severe sepsis. The etiology of liver disease due to infections includes bacteria, virus, yeast and parasites. The frequency of the different mentioned pathogens is related to both the geographic location and the immunologic condition of the host. This review is focused on liver manifestations during different systemic infections as well as the liver involvement in the most common opportunistic infections in HIV patients." @default.
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- W2344897488 date "2016-04-01" @default.
- W2344897488 modified "2023-10-16" @default.
- W2344897488 title "Afectación hepática en enfermedades infecciosas. Hepatopatías en pacientes inmunodeficientes" @default.
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- W2344897488 doi "https://doi.org/10.1016/j.med.2016.04.004" @default.
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