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• W2344918478 abstract "Traumatic brain injuries (TBI) often involve vascular dysfunction that leads to long-term alterations in physiological and cognitive functions of the brain. Indeed, all the cells that form blood vessels and that are involved in maintaining their proper function can be altered by TBI. This Review focuses on the different types of cerebrovascular dysfunction that occur after TBI, including cerebral blood flow alterations, autoregulation impairments, subarachnoid hemorrhage, vasospasms, blood-brain barrier disruption, and edema formation. We also discuss the mechanisms that mediate these dysfunctions, focusing on the cellular components of cerebral blood vessels (endothelial cells, smooth muscle cells, astrocytes, pericytes, perivascular nerves) and their known and potential roles in the secondary injury cascade. © 2016 Wiley Periodicals, Inc." @default.
• W2344918478 created "2016-06-24" @default.
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• W2344918478 creator A5077139153 @default.
• W2344918478 creator A5082259652 @default.
• W2344918478 date "2016-04-27" @default.
• W2344918478 modified "2023-10-04" @default.
• W2344918478 title "Chronic cerebrovascular dysfunction after traumatic brain injury" @default.
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