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- W2345103282 abstract "目的：探讨D-二聚体（DD）／FDP比值对新生儿弥散性血管内凝血前期（preDIC）的诊断及治疗意义。方法：对NICU收治的96例危重新生儿中符合preDIC临床诊断标准的48例（preDIC组）和DIC的48例（DIC组）及50例正常新生儿（对照组）检测其血清中DD、FDP及DD／FDP的水平，以及应用小剂量肝素后preDIC组和DIC组血清中DD、FDP、DD／FDP的水平变化。结果：preDIC组和DIC组中DD、FDP均有明显升高，与对照组比较差异有统计学意义（P〈0．05），preDIC组和DIC组比较差异无统计学意义（P〉0．05）；preDIC组中DD／FDP比值较DIC组比值明显升高，差异有统计学意义（P〈0．05）；应用小剂量肝素后，preDIC组与DIC组中DD、FDP水平均明显下降，两组比较差异无统计学意义（P〉0．05）；preDIC组中DD／FDP明显下降，肝素应用前后比较差异有统计学意义（P〈0．05），DIC组前后比较差异无统计学意义（P〉0．05）。结论：在DIC前期，凝血系统和纤溶系统均已发生明显改变，且凝血功能明显要高于其纤溶功能，故监测DD／FDP比值有助于DIC前期的诊断；在应用小剂量肝素后比值明显下降，有助于早期阻止DIC的发生。" @default.
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- W2345103282 date "2012-01-01" @default.
- W2345103282 modified "2023-09-24" @default.
- W2345103282 title "D-二聚体／FDP比值在新生儿弥散性血管内凝血前期诊治中的意义" @default.
- W2345103282 hasPublicationYear "2012" @default.
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