FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2345338575> ?p ?o ?g. }

• W2345338575 endingPage "903" @default.
• W2345338575 startingPage "895" @default.
• W2345338575 abstract "Condensation of 4,5‐diaminopyrimidines 2 and 3 with 2,2ʹ‐dipyridil ( 4 ) afforded 6,7‐bis(2‐pyridyl)pteridine‐2‐one analogues 5 and 7 , respectively. Analogously, 6,7‐bis(2‐pyridyl)luamzine derivatives 13 , 15 , 17 , and 23 were synthesized from reaction of 5,6‐diamino‐2‐thiopyrimidines 13 , 14 , and 22 with 4 , respectively, while condensation of 4,5,6‐triaminopyrimidines ( 25 ) or 5,6‐diamino analogue 26 with 4 furnished the 4‐amino‐pteridine analogue 27 and 28 , respectively. Thiation of the new pteridines and lumazines afforded the 4‐thio analogues 6 , 8 , 16 , and 24 . Treatment of 6 and 8 with methanolic ammonia afforded the 4‐isopterine analogues 9 and 10 , respectively. Alkylation of 15 with substituted phenacyl chloride furnished 18 and 19 , which cyclized to the thiazolo‐pteridine derivatives 20 and 21 , respectively, on treatment with polyphosphoric acid. Alternatively, 27 was prepared from treatment of 24 with methanolic ammonia under drastic conditions. Condensation of 2 or 29 with 2‐oxo‐2‐(thiophen‐2‐yl)acetaldehyde oxime ( 11 ) gave the 6‐(2‐thienyl)‐pteridine‐4‐one ( 12 ) and 5‐chloro‐2‐(2‐thienyl)pyrido[3,4‐ b ]pyrazine ( 31 ), respectively. All compounds were evaluated for their antiviral activity against the replication of HIV‐1 and HIV‐2 in MT‐4. Some of the synthesized compounds were tested against the bacterial species, Escherichia coli and Staphylococcus aureus , as well as fungal species, Candida tropicalis and Candida albicans ." @default.
• W2345338575 created "2016-06-24" @default.
• W2345338575 creator A5013005081 @default.
• W2345338575 creator A5055902445 @default.
• W2345338575 creator A5087457661 @default.
• W2345338575 creator A5089399031 @default.
• W2345338575 date "2016-05-03" @default.
• W2345338575 modified "2023-10-05" @default.
• W2345338575 title "Synthesis and Biological Evaluation of New Dipyridylpteridines, Lumazines, and Related Analogues" @default.
• W2345338575 cites W1883308443 @default.
• W2345338575 cites W1965765803 @default.
• W2345338575 cites W1991519292 @default.
• W2345338575 cites W1999467850 @default.
• W2345338575 cites W2001886067 @default.
• W2345338575 cites W2012525588 @default.
• W2345338575 cites W2017380386 @default.
• W2345338575 cites W2018708925 @default.
• W2345338575 cites W2020931705 @default.
• W2345338575 cites W2025773275 @default.
• W2345338575 cites W2032531732 @default.
• W2345338575 cites W2038188866 @default.
• W2345338575 cites W2039934783 @default.
• W2345338575 cites W2040194232 @default.
• W2345338575 cites W2041746801 @default.
• W2345338575 cites W2041850496 @default.
• W2345338575 cites W2048179618 @default.
• W2345338575 cites W2060332800 @default.
• W2345338575 cites W2068174812 @default.
• W2345338575 cites W2079567283 @default.
• W2345338575 cites W2096846691 @default.
• W2345338575 cites W2102686696 @default.
• W2345338575 cites W2104316189 @default.
• W2345338575 cites W2108366063 @default.
• W2345338575 cites W2109375527 @default.
• W2345338575 cites W2141112342 @default.
• W2345338575 cites W2143132863 @default.
• W2345338575 cites W2154319103 @default.
• W2345338575 cites W2168986531 @default.
• W2345338575 cites W2180765374 @default.
• W2345338575 cites W2345970135 @default.
• W2345338575 cites W2949241553 @default.
• W2345338575 cites W2950197021 @default.
• W2345338575 cites W2952675088 @default.
• W2345338575 doi "https://doi.org/10.1002/jhet.2651" @default.
• W2345338575 hasPublicationYear "2016" @default.
• W2345338575 type Work @default.
• W2345338575 sameAs 2345338575 @default.
• W2345338575 citedByCount "7" @default.
• W2345338575 countsByYear W23453385752016 @default.
• W2345338575 countsByYear W23453385752018 @default.
• W2345338575 countsByYear W23453385752019 @default.
• W2345338575 countsByYear W23453385752021 @default.
• W2345338575 countsByYear W23453385752022 @default.
• W2345338575 crossrefType "journal-article" @default.
• W2345338575 hasAuthorship W2345338575A5013005081 @default.
• W2345338575 hasAuthorship W2345338575A5055902445 @default.
• W2345338575 hasAuthorship W2345338575A5087457661 @default.
• W2345338575 hasAuthorship W2345338575A5089399031 @default.
• W2345338575 hasConcept C155647269 @default.
• W2345338575 hasConcept C178790620 @default.
• W2345338575 hasConcept C181199279 @default.
• W2345338575 hasConcept C185592680 @default.
• W2345338575 hasConcept C2776275976 @default.
• W2345338575 hasConcept C2776382133 @default.
• W2345338575 hasConcept C2777765701 @default.
• W2345338575 hasConcept C2778324468 @default.
• W2345338575 hasConcept C2779321679 @default.
• W2345338575 hasConcept C2779648554 @default.
• W2345338575 hasConcept C2780570554 @default.
• W2345338575 hasConcept C2781253882 @default.
• W2345338575 hasConcept C71240020 @default.
• W2345338575 hasConceptScore W2345338575C155647269 @default.
• W2345338575 hasConceptScore W2345338575C178790620 @default.
• W2345338575 hasConceptScore W2345338575C181199279 @default.
• W2345338575 hasConceptScore W2345338575C185592680 @default.
• W2345338575 hasConceptScore W2345338575C2776275976 @default.
• W2345338575 hasConceptScore W2345338575C2776382133 @default.
• W2345338575 hasConceptScore W2345338575C2777765701 @default.
• W2345338575 hasConceptScore W2345338575C2778324468 @default.
• W2345338575 hasConceptScore W2345338575C2779321679 @default.
• W2345338575 hasConceptScore W2345338575C2779648554 @default.
• W2345338575 hasConceptScore W2345338575C2780570554 @default.
• W2345338575 hasConceptScore W2345338575C2781253882 @default.
• W2345338575 hasConceptScore W2345338575C71240020 @default.
• W2345338575 hasIssue "2" @default.
• W2345338575 hasLocation W23453385751 @default.
• W2345338575 hasOpenAccess W2345338575 @default.
• W2345338575 hasPrimaryLocation W23453385751 @default.
• W2345338575 hasRelatedWork W2005292050 @default.
• W2345338575 hasRelatedWork W2023169139 @default.
• W2345338575 hasRelatedWork W2023275187 @default.
• W2345338575 hasRelatedWork W2033661613 @default.
• W2345338575 hasRelatedWork W2036130506 @default.
• W2345338575 hasRelatedWork W2065331739 @default.
• W2345338575 hasRelatedWork W2068130490 @default.
• W2345338575 hasRelatedWork W2321107077 @default.
• W2345338575 hasRelatedWork W2345338575 @default.
• W2345338575 hasRelatedWork W2399039609 @default.

• next