FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2345491132> ?p ?o ?g. }

• W2345491132 endingPage "6" @default.
• W2345491132 startingPage "1312" @default.
• W2345491132 abstract "The effects of cisapride and renzapride (BRL 24924), on plasma concentration of motilin and gastroduodenal motility were studied in seven dogs with implanted force transducers in the antrum and duodenum. In the interdigestive state, the i.v. administration of cisapride (5 mg) or renzapride (5 mg) administered in phase I resulted in a prompt and marked increase in plasma motilin concentration and in gastroduodenal motility. Mean plasma motilin levels during the first 30 min after cisapride and after renzapride injection were 85.0 +/- 6.5 (+/- S.E.) and 96.1 +/- 6.3 pM., respectively. These values were significantly greater (P < .001) than those for the corresponding time period of the control cycle, 52.2 +/- 5.6 and 57.4 +/- 5.3 pM (mean phase III level, 120 +/- 8.1 pM), respectively. The increases in the motilin level after cisapride or renzapride coincided with significant increases in contractile activities of the antrum to 43.2 +/- 5.3% and 44.9 +/- 4.6% and of the duodenum to 28.4 +/- 3.1% and 34.2 +/- 2.2% of phase III activity (100%) from that in the corresponding control period, 0.7 +/- 0.4% and 0.2 +/- 0.1%, respectively. The changes in both plasma motilin and motility in response to the two drugs were abolished completely by the i.v. administration of atropine. The drugs also enhanced the meal-induced contractile activities of the antrum as well as the duodenum but failed to influence the postprandial plasma motilin concentration. We conclude that cisapride and renzapride have similar effects on plasma motilin and gastroduodenal motility: 1) the two drugs increase plasma motilin levels and stimulate gastroduodenal motility in the interdigestive state, and 2) in the digestive state, both drugs enhance motility without influencing the plasma motilin levels." @default.
• W2345491132 created "2016-06-24" @default.
• W2345491132 creator A5001492813 @default.
• W2345491132 creator A5001915400 @default.
• W2345491132 creator A5045259947 @default.
• W2345491132 creator A5086869103 @default.
• W2345491132 creator A5087837735 @default.
• W2345491132 date "1997-06-01" @default.
• W2345491132 modified "2023-09-29" @default.
• W2345491132 title "Effect of cisapride and renzapride on gastrointestinal motility and plasma motilin concentration in dogs." @default.
• W2345491132 cites W10643936 @default.
• W2345491132 cites W1497740316 @default.
• W2345491132 cites W1503293110 @default.
• W2345491132 cites W1907248341 @default.
• W2345491132 cites W1969377544 @default.
• W2345491132 cites W1976781959 @default.
• W2345491132 cites W1983211936 @default.
• W2345491132 cites W1994849282 @default.
• W2345491132 cites W1998895541 @default.
• W2345491132 cites W2014911788 @default.
• W2345491132 cites W2022714001 @default.
• W2345491132 cites W2034454457 @default.
• W2345491132 cites W2034970442 @default.
• W2345491132 cites W2046045403 @default.
• W2345491132 cites W2059306368 @default.
• W2345491132 cites W2059472676 @default.
• W2345491132 cites W2076826596 @default.
• W2345491132 cites W2076868118 @default.
• W2345491132 cites W2079847691 @default.
• W2345491132 cites W2080111908 @default.
• W2345491132 cites W2084555557 @default.
• W2345491132 cites W2094089660 @default.
• W2345491132 cites W2107672748 @default.
• W2345491132 cites W2148192712 @default.
• W2345491132 cites W2164245190 @default.
• W2345491132 cites W2172339334 @default.
• W2345491132 cites W2224802806 @default.
• W2345491132 cites W2232346553 @default.
• W2345491132 cites W2240282767 @default.
• W2345491132 cites W2262005417 @default.
• W2345491132 cites W2409158375 @default.
• W2345491132 cites W2414029373 @default.
• W2345491132 cites W2426880131 @default.
• W2345491132 cites W2460684159 @default.
• W2345491132 cites W2474937170 @default.
• W2345491132 cites W257741065 @default.
• W2345491132 cites W3146425672 @default.
• W2345491132 cites W827905170 @default.
• W2345491132 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9190867" @default.
• W2345491132 hasPublicationYear "1997" @default.
• W2345491132 type Work @default.
• W2345491132 sameAs 2345491132 @default.
• W2345491132 citedByCount "5" @default.
• W2345491132 crossrefType "journal-article" @default.
• W2345491132 hasAuthorship W2345491132A5001492813 @default.
• W2345491132 hasAuthorship W2345491132A5001915400 @default.
• W2345491132 hasAuthorship W2345491132A5045259947 @default.
• W2345491132 hasAuthorship W2345491132A5086869103 @default.
• W2345491132 hasAuthorship W2345491132A5087837735 @default.
• W2345491132 hasConcept C126322002 @default.
• W2345491132 hasConcept C131253125 @default.
• W2345491132 hasConcept C131793682 @default.
• W2345491132 hasConcept C134018914 @default.
• W2345491132 hasConcept C2776119469 @default.
• W2345491132 hasConcept C2776809568 @default.
• W2345491132 hasConcept C2778199505 @default.
• W2345491132 hasConcept C2779306644 @default.
• W2345491132 hasConcept C2779422922 @default.
• W2345491132 hasConcept C54355233 @default.
• W2345491132 hasConcept C58207958 @default.
• W2345491132 hasConcept C71924100 @default.
• W2345491132 hasConcept C86803240 @default.
• W2345491132 hasConceptScore W2345491132C126322002 @default.
• W2345491132 hasConceptScore W2345491132C131253125 @default.
• W2345491132 hasConceptScore W2345491132C131793682 @default.
• W2345491132 hasConceptScore W2345491132C134018914 @default.
• W2345491132 hasConceptScore W2345491132C2776119469 @default.
• W2345491132 hasConceptScore W2345491132C2776809568 @default.
• W2345491132 hasConceptScore W2345491132C2778199505 @default.
• W2345491132 hasConceptScore W2345491132C2779306644 @default.
• W2345491132 hasConceptScore W2345491132C2779422922 @default.
• W2345491132 hasConceptScore W2345491132C54355233 @default.
• W2345491132 hasConceptScore W2345491132C58207958 @default.
• W2345491132 hasConceptScore W2345491132C71924100 @default.
• W2345491132 hasConceptScore W2345491132C86803240 @default.
• W2345491132 hasIssue "3" @default.
• W2345491132 hasLocation W23454911321 @default.
• W2345491132 hasOpenAccess W2345491132 @default.
• W2345491132 hasPrimaryLocation W23454911321 @default.
• W2345491132 hasRelatedWork W1968896868 @default.
• W2345491132 hasRelatedWork W1982291147 @default.
• W2345491132 hasRelatedWork W2006177548 @default.
• W2345491132 hasRelatedWork W2022080162 @default.
• W2345491132 hasRelatedWork W2086340847 @default.
• W2345491132 hasRelatedWork W2105130582 @default.
• W2345491132 hasRelatedWork W2326889965 @default.
• W2345491132 hasRelatedWork W2345491132 @default.
• W2345491132 hasRelatedWork W24906095 @default.

• next