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• W2345542347 endingPage "1670" @default.
• W2345542347 startingPage "1667" @default.
• W2345542347 abstract "Early T‐cell precursor acute lymphoblastic leukemia (ETP‐ALL) is a subtype of T‐acute lymphoblastic leukemia (T‐ALL) arising from a primitive precursor. We present a unique case of an infant with ETP‐ALL with a missense NRAS mutation in codon 61 (c.182A>G, p.Q61R). The patient also had a minor population of non‐ETP T‐ALL blasts and clinical features typically associated with juvenile myelomonocytic leukemia (JMML), namely, absolute monocytosis, splenomegaly, and elevated hemoglobin F. The treatment was initiated with chemotherapy, followed by cord blood transplantation. The patient achieved remission, but unfortunately died from transplant‐related complications. This case highlights an NRAS mutation in ETP‐ALL with JMML‐like phenotype." @default.
• W2345542347 created "2016-06-24" @default.
• W2345542347 creator A5013754928 @default.
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• W2345542347 date "2016-05-04" @default.
• W2345542347 modified "2023-09-27" @default.
• W2345542347 title "Early T-Cell Precursor Acute Lymphoblastic Leukemia in an Infant With an<i>NRAS</i>Q61R Mutation and Clinical Features of Juvenile Myelomonocytic Leukemia" @default.
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• W2345542347 doi "https://doi.org/10.1002/pbc.26050" @default.
• W2345542347 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27145535" @default.
• W2345542347 hasPublicationYear "2016" @default.
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