FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2346154262> ?p ?o ?g. }

• W2346154262 abstract "Parental exposure to an environmental challenge can induce phenotypes in offspring independent of the inherited DNA sequence. Whether such acquired traits can be inherited, i.e., can manifest in a generation beyond that exposed to the precipitating insult as germ cells, is unclear. Here we report a latent metabolic phenotype induced by paternal obesity that is inherited into a second generation, without germ cell exposure. Sons of obese male mice exhibit defects in glucose and lipid metabolism that are only unmasked by post-weaning dietary challenge, yet they transmit these defects to their own progeny (F2) in the absence of the challenge. F1 sperm exhibit changes in the abundance of several small RNA species, including diet responsive tRNA-derived fragments. These data suggest that induced metabolic phenotypes may be propagated for multiple generations through the actions of noncoding RNA." @default.
• W2346154262 created "2016-06-24" @default.
• W2346154262 creator A5007553024 @default.
• W2346154262 creator A5009054460 @default.
• W2346154262 creator A5012268284 @default.
• W2346154262 creator A5024964336 @default.
• W2346154262 creator A5030539741 @default.
• W2346154262 creator A5037202934 @default.
• W2346154262 creator A5043876050 @default.
• W2346154262 creator A5059782001 @default.
• W2346154262 creator A5068661059 @default.
• W2346154262 creator A5068732085 @default.
• W2346154262 creator A5069541167 @default.
• W2346154262 creator A5070112085 @default.
• W2346154262 creator A5078579946 @default.
• W2346154262 creator A5088295276 @default.
• W2346154262 creator A5088453866 @default.
• W2346154262 date "2016-03-10" @default.
• W2346154262 modified "2023-10-12" @default.
• W2346154262 title "Grand paternal inheritance of an acquired metabolic trait induced by ancestral obesity is associated with sperm RNA" @default.
• W2346154262 cites W1762126634 @default.
• W2346154262 cites W1973939264 @default.
• W2346154262 cites W1976684529 @default.
• W2346154262 cites W1995363107 @default.
• W2346154262 cites W2028212562 @default.
• W2346154262 cites W2032640887 @default.
• W2346154262 cites W2035074912 @default.
• W2346154262 cites W2037108634 @default.
• W2346154262 cites W2044794679 @default.
• W2346154262 cites W2057056702 @default.
• W2346154262 cites W2059632047 @default.
• W2346154262 cites W2065973763 @default.
• W2346154262 cites W2068271232 @default.
• W2346154262 cites W2082246284 @default.
• W2346154262 cites W2083381199 @default.
• W2346154262 cites W2087921665 @default.
• W2346154262 cites W2089567564 @default.
• W2346154262 cites W2090723511 @default.
• W2346154262 cites W2097331197 @default.
• W2346154262 cites W2101524853 @default.
• W2346154262 cites W2114104545 @default.
• W2346154262 cites W2119477130 @default.
• W2346154262 cites W2122827135 @default.
• W2346154262 cites W2122984483 @default.
• W2346154262 cites W2123363267 @default.
• W2346154262 cites W2124770148 @default.
• W2346154262 cites W2130597092 @default.
• W2346154262 cites W2133465414 @default.
• W2346154262 cites W2133824155 @default.
• W2346154262 cites W2134868253 @default.
• W2346154262 cites W2135007810 @default.
• W2346154262 cites W2135802673 @default.
• W2346154262 cites W2137291580 @default.
• W2346154262 cites W2141384633 @default.
• W2346154262 cites W2146974028 @default.
• W2346154262 cites W2148258489 @default.
• W2346154262 cites W2157193551 @default.
• W2346154262 cites W2157917165 @default.
• W2346154262 cites W2158217645 @default.
• W2346154262 cites W2161536630 @default.
• W2346154262 cites W2166236051 @default.
• W2346154262 cites W2170654934 @default.
• W2346154262 cites W2201382378 @default.
• W2346154262 cites W2210080033 @default.
• W2346154262 doi "https://doi.org/10.1101/042101" @default.
• W2346154262 hasPublicationYear "2016" @default.
• W2346154262 type Work @default.
• W2346154262 sameAs 2346154262 @default.
• W2346154262 citedByCount "2" @default.
• W2346154262 countsByYear W23461542622016 @default.
• W2346154262 crossrefType "posted-content" @default.
• W2346154262 hasAuthorship W2346154262A5007553024 @default.
• W2346154262 hasAuthorship W2346154262A5009054460 @default.
• W2346154262 hasAuthorship W2346154262A5012268284 @default.
• W2346154262 hasAuthorship W2346154262A5024964336 @default.
• W2346154262 hasAuthorship W2346154262A5030539741 @default.
• W2346154262 hasAuthorship W2346154262A5037202934 @default.
• W2346154262 hasAuthorship W2346154262A5043876050 @default.
• W2346154262 hasAuthorship W2346154262A5059782001 @default.
• W2346154262 hasAuthorship W2346154262A5068661059 @default.
• W2346154262 hasAuthorship W2346154262A5068732085 @default.
• W2346154262 hasAuthorship W2346154262A5069541167 @default.
• W2346154262 hasAuthorship W2346154262A5070112085 @default.
• W2346154262 hasAuthorship W2346154262A5078579946 @default.
• W2346154262 hasAuthorship W2346154262A5088295276 @default.
• W2346154262 hasAuthorship W2346154262A5088453866 @default.
• W2346154262 hasBestOaLocation W23461542621 @default.
• W2346154262 hasConcept C104317684 @default.
• W2346154262 hasConcept C106934330 @default.
• W2346154262 hasConcept C112672928 @default.
• W2346154262 hasConcept C127716648 @default.
• W2346154262 hasConcept C134305767 @default.
• W2346154262 hasConcept C153957851 @default.
• W2346154262 hasConcept C199360897 @default.
• W2346154262 hasConcept C24586158 @default.
• W2346154262 hasConcept C2779122487 @default.
• W2346154262 hasConcept C2779234561 @default.
• W2346154262 hasConcept C2781087480 @default.
• W2346154262 hasConcept C41008148 @default.
• W2346154262 hasConcept C54355233 @default.

• next