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• W2346202365 abstract "The effects of insulin on porcine thecal steroidogenesis were examined in long-term cultures of hyaluronidase-collagenase dispersed thecal cells. The thecal cultures made significant amounts of progesterone (P) and androstenedione (∆4A). Testosterone, dihydrotestosterone, estrone, and estradiol could not be detected in the media. Luteinizing hormone (LH) alone significantly increased P and ∆4A accumulation. Insulin alone increased P accumulation on days 2 to 4 of culture. Insulin alone did not stimulate ∆4A accumulation. Insulin plus LH resulted in a significantly greater accumulation of P and ∆4A than LH alone. These results suggest that insulin may be a regulator of ovarian thecal steroidogenesis." @default.
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• W2346202365 date "1983-08-01" @default.
• W2346202365 modified "2023-09-27" @default.
• W2346202365 title "Effects of insulin on steroidogenesis in cultured porcine ovarian theca" @default.
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• W2346202365 doi "https://doi.org/10.1016/s0015-0282(16)47243-2" @default.
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