Matches in SemOpenAlex for { <https://semopenalex.org/work/W2346309595> ?p ?o ?g. }
- W2346309595 endingPage "436" @default.
- W2346309595 startingPage "424" @default.
- W2346309595 abstract "CURLY LEAF (CLF), a histone methyltransferase of Polycomb Repressive Complex 2 (PRC2) for trimethylation of histone H3 Lys 27 (H3K27me3), has been thought as a negative regulator controlling mainly postgermination growth in Arabidopsis (Arabidopsis thaliana). Approximately 14% to 29% of genic regions are decorated by H3K27me3 in the Arabidopsis genome; however, transcriptional repression activities of PRC2 on a majority of these regions remain unclear. Here, by analysis of transcriptome profiles, we found that approximately 11.6% genes in the Arabidopsis genome were repressed by CLF in various organs. Unexpectedly, approximately 54% of these genes were preferentially repressed in siliques. Further analyses of 118 transcriptome datasets uncovered a group of genes that was preferentially expressed and repressed by CLF in embryos at the mature-green stage. This observation suggests that CLF mediates a large-scale H3K27me3 programming/reprogramming event during embryonic development. Plants of clf-28 produced bigger and heavier seeds with higher oil content, larger oil bodies, and altered long-chain fatty acid composition compared with wild type. Around 46% of CLF-repressed genes were associated with H3K27me3 marks; moreover, we verified histone modification and transcriptional repression by CLF on regulatory genes. Our results suggest that CLF silences specific gene expression modules. Genes operating within a module have various molecular functions, but they cooperate to regulate a similar physiological function during embryo development." @default.
- W2346309595 created "2016-06-24" @default.
- W2346309595 creator A5009988205 @default.
- W2346309595 creator A5050424155 @default.
- W2346309595 creator A5062435885 @default.
- W2346309595 creator A5063853997 @default.
- W2346309595 creator A5065168048 @default.
- W2346309595 creator A5071640719 @default.
- W2346309595 creator A5083443756 @default.
- W2346309595 date "2016-03-04" @default.
- W2346309595 modified "2023-10-16" @default.
- W2346309595 title "<i>CURLY LEAF</i> Regulates Gene Sets Coordinating Seed Size and Lipid Biosynthesis" @default.
- W2346309595 cites W1509359129 @default.
- W2346309595 cites W1963736125 @default.
- W2346309595 cites W1965013480 @default.
- W2346309595 cites W1966697893 @default.
- W2346309595 cites W1967656072 @default.
- W2346309595 cites W1971561248 @default.
- W2346309595 cites W1982720588 @default.
- W2346309595 cites W1984249602 @default.
- W2346309595 cites W1988107840 @default.
- W2346309595 cites W1991270273 @default.
- W2346309595 cites W1992048026 @default.
- W2346309595 cites W1998918762 @default.
- W2346309595 cites W1999078614 @default.
- W2346309595 cites W2002557938 @default.
- W2346309595 cites W2007041216 @default.
- W2346309595 cites W2008798240 @default.
- W2346309595 cites W2010671327 @default.
- W2346309595 cites W2015246122 @default.
- W2346309595 cites W2025040226 @default.
- W2346309595 cites W2025579230 @default.
- W2346309595 cites W2037548653 @default.
- W2346309595 cites W2040490059 @default.
- W2346309595 cites W2042088824 @default.
- W2346309595 cites W2045299822 @default.
- W2346309595 cites W2047284611 @default.
- W2346309595 cites W2051852571 @default.
- W2346309595 cites W2053943338 @default.
- W2346309595 cites W2058633496 @default.
- W2346309595 cites W2063947061 @default.
- W2346309595 cites W2064204789 @default.
- W2346309595 cites W2082276197 @default.
- W2346309595 cites W2085932408 @default.
- W2346309595 cites W2088348237 @default.
- W2346309595 cites W2088998472 @default.
- W2346309595 cites W2090144085 @default.
- W2346309595 cites W2090897705 @default.
- W2346309595 cites W2092442147 @default.
- W2346309595 cites W2094032514 @default.
- W2346309595 cites W2095166254 @default.
- W2346309595 cites W2096561521 @default.
- W2346309595 cites W2097065948 @default.
- W2346309595 cites W2098115340 @default.
- W2346309595 cites W2102619694 @default.
- W2346309595 cites W2102996707 @default.
- W2346309595 cites W2103793524 @default.
- W2346309595 cites W2104864984 @default.
- W2346309595 cites W2107366172 @default.
- W2346309595 cites W2108234281 @default.
- W2346309595 cites W2109604687 @default.
- W2346309595 cites W2111407873 @default.
- W2346309595 cites W2112894735 @default.
- W2346309595 cites W2114527699 @default.
- W2346309595 cites W2117199973 @default.
- W2346309595 cites W2120865735 @default.
- W2346309595 cites W2137743358 @default.
- W2346309595 cites W2141458291 @default.
- W2346309595 cites W2144235605 @default.
- W2346309595 cites W2146440424 @default.
- W2346309595 cites W2149935837 @default.
- W2346309595 cites W2152239989 @default.
- W2346309595 cites W2155201905 @default.
- W2346309595 cites W2155990718 @default.
- W2346309595 cites W2157104689 @default.
- W2346309595 cites W2157897524 @default.
- W2346309595 cites W2161397498 @default.
- W2346309595 cites W2162080206 @default.
- W2346309595 cites W2164519838 @default.
- W2346309595 cites W2167827709 @default.
- W2346309595 cites W2167865654 @default.
- W2346309595 cites W2168728371 @default.
- W2346309595 cites W2170551349 @default.
- W2346309595 cites W2171808845 @default.
- W2346309595 cites W2172186075 @default.
- W2346309595 doi "https://doi.org/10.1104/pp.15.01335" @default.
- W2346309595 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4854673" @default.
- W2346309595 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26945048" @default.
- W2346309595 hasPublicationYear "2016" @default.
- W2346309595 type Work @default.
- W2346309595 sameAs 2346309595 @default.
- W2346309595 citedByCount "54" @default.
- W2346309595 countsByYear W23463095952016 @default.
- W2346309595 countsByYear W23463095952017 @default.
- W2346309595 countsByYear W23463095952018 @default.
- W2346309595 countsByYear W23463095952019 @default.
- W2346309595 countsByYear W23463095952020 @default.
- W2346309595 countsByYear W23463095952021 @default.