FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2346417148> ?p ?o ?g. }

• W2346417148 abstract "Invasive meningococcal disease is a serious infection that is most often vaccine-preventable. Long-term protection relies on antibody persistence. Here we report the persistence of the immune response 2 y post-vaccination with a quadrivalent meningococcal serogroups A, C, W, Y tetanus toxoid conjugate vaccine (MenACWY-TT) compared with a MenACWY polysaccharide vaccine (Men-PS), in Asian adolescents aged 11-17 y. We also report a re-analysis of data from the primary vaccination study. This persistence study (NCT00974363) conducted in India and the Philippines included subjects who previously (study NCT00464815) received a single dose of MenACWY-TT or Men-PS. Persistence of functional antibodies was measured in 407 MenACWY-TT recipients and 132 Men-PS recipients (according-to-protocol cohort) using a rabbit complement serum bactericidal assay (rSBA, cut-off 1:8). Vaccine-related serious adverse events (SAEs) occurring since the end of the initial vaccination study were retrospectively recorded. Two y post-vaccination ≥99.3% of adolescents who received MenACWY-TT had persisting antibody titers ≥1:8 against each vaccine serogroup. Antibody persistence was higher (exploratory analysis) in the MenACWY-TT group than the Men-PS group in terms of rSBA titers ≥1:8 for serogroups W and Y; rSBA titers ≥1:128 for serogroups A, W and Y; and rSBA GMTs for serogroups A, W and Y; and was lower in the MenACWY-TT group for rSBA GMTs for serogroup C. No vaccine-related SAEs were reported. The results of this study indicated that antibodies persisted for at least 2 y in the majority of adolescents after vaccination with a single dose of MenACWY-TT." @default.
• W2346417148 created "2016-06-24" @default.
• W2346417148 creator A5009701640 @default.
• W2346417148 creator A5015954272 @default.
• W2346417148 creator A5026349633 @default.
• W2346417148 creator A5047138862 @default.
• W2346417148 creator A5060209498 @default.
• W2346417148 creator A5060243025 @default.
• W2346417148 creator A5060640852 @default.
• W2346417148 creator A5067123101 @default.
• W2346417148 date "2016-05-06" @default.
• W2346417148 modified "2023-09-23" @default.
• W2346417148 title "Persistence of the immune response two years after vaccination with quadrivalent meningococcal ACWY-tetanus toxoid conjugate vaccine (MenACWY-TT) in Asian adolescents" @default.
• W2346417148 cites W1912692997 @default.
• W2346417148 cites W1964804247 @default.
• W2346417148 cites W1965328620 @default.
• W2346417148 cites W1976058654 @default.
• W2346417148 cites W1976717129 @default.
• W2346417148 cites W1978153776 @default.
• W2346417148 cites W1986910419 @default.
• W2346417148 cites W1987029428 @default.
• W2346417148 cites W1989485865 @default.
• W2346417148 cites W2005063593 @default.
• W2346417148 cites W2015856862 @default.
• W2346417148 cites W2020628200 @default.
• W2346417148 cites W2031697639 @default.
• W2346417148 cites W2033366028 @default.
• W2346417148 cites W2037298804 @default.
• W2346417148 cites W2038529633 @default.
• W2346417148 cites W2046191981 @default.
• W2346417148 cites W2071212938 @default.
• W2346417148 cites W2071305953 @default.
• W2346417148 cites W2073729165 @default.
• W2346417148 cites W2082705433 @default.
• W2346417148 cites W2095551099 @default.
• W2346417148 cites W2128589740 @default.
• W2346417148 cites W2129920904 @default.
• W2346417148 cites W2137586712 @default.
• W2346417148 cites W2140617263 @default.
• W2346417148 cites W2148938842 @default.
• W2346417148 cites W2153093505 @default.
• W2346417148 cites W2171902734 @default.
• W2346417148 cites W4251810123 @default.
• W2346417148 doi "https://doi.org/10.1080/21645515.2016.1163455" @default.
• W2346417148 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4994734" @default.
• W2346417148 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27152501" @default.
• W2346417148 hasPublicationYear "2016" @default.
• W2346417148 type Work @default.
• W2346417148 sameAs 2346417148 @default.
• W2346417148 citedByCount "4" @default.
• W2346417148 countsByYear W23464171482017 @default.
• W2346417148 countsByYear W23464171482019 @default.
• W2346417148 countsByYear W23464171482020 @default.
• W2346417148 crossrefType "journal-article" @default.
• W2346417148 hasAuthorship W2346417148A5009701640 @default.
• W2346417148 hasAuthorship W2346417148A5015954272 @default.
• W2346417148 hasAuthorship W2346417148A5026349633 @default.
• W2346417148 hasAuthorship W2346417148A5047138862 @default.
• W2346417148 hasAuthorship W2346417148A5060209498 @default.
• W2346417148 hasAuthorship W2346417148A5060243025 @default.
• W2346417148 hasAuthorship W2346417148A5060640852 @default.
• W2346417148 hasAuthorship W2346417148A5067123101 @default.
• W2346417148 hasBestOaLocation W23464171481 @default.
• W2346417148 hasConcept C126322002 @default.
• W2346417148 hasConcept C127413603 @default.
• W2346417148 hasConcept C159654299 @default.
• W2346417148 hasConcept C187212893 @default.
• W2346417148 hasConcept C187320778 @default.
• W2346417148 hasConcept C197934379 @default.
• W2346417148 hasConcept C203014093 @default.
• W2346417148 hasConcept C22070199 @default.
• W2346417148 hasConcept C2777351567 @default.
• W2346417148 hasConcept C2779583294 @default.
• W2346417148 hasConcept C2779841045 @default.
• W2346417148 hasConcept C2780454893 @default.
• W2346417148 hasConcept C2780801004 @default.
• W2346417148 hasConcept C2781009140 @default.
• W2346417148 hasConcept C2781026528 @default.
• W2346417148 hasConcept C32611913 @default.
• W2346417148 hasConcept C71924100 @default.
• W2346417148 hasConceptScore W2346417148C126322002 @default.
• W2346417148 hasConceptScore W2346417148C127413603 @default.
• W2346417148 hasConceptScore W2346417148C159654299 @default.
• W2346417148 hasConceptScore W2346417148C187212893 @default.
• W2346417148 hasConceptScore W2346417148C187320778 @default.
• W2346417148 hasConceptScore W2346417148C197934379 @default.
• W2346417148 hasConceptScore W2346417148C203014093 @default.
• W2346417148 hasConceptScore W2346417148C22070199 @default.
• W2346417148 hasConceptScore W2346417148C2777351567 @default.
• W2346417148 hasConceptScore W2346417148C2779583294 @default.
• W2346417148 hasConceptScore W2346417148C2779841045 @default.
• W2346417148 hasConceptScore W2346417148C2780454893 @default.
• W2346417148 hasConceptScore W2346417148C2780801004 @default.
• W2346417148 hasConceptScore W2346417148C2781009140 @default.
• W2346417148 hasConceptScore W2346417148C2781026528 @default.
• W2346417148 hasConceptScore W2346417148C32611913 @default.
• W2346417148 hasConceptScore W2346417148C71924100 @default.
• W2346417148 hasLocation W23464171481 @default.
• W2346417148 hasLocation W23464171482 @default.
• W2346417148 hasLocation W23464171483 @default.

• next