Matches in SemOpenAlex for { <https://semopenalex.org/work/W2346644876> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2346644876 endingPage "8418" @default.
- W2346644876 startingPage "8411" @default.
- W2346644876 abstract "The effect of Eruca sativa seed extract (SE) on nuclear factor kappa B (NF-<TEX>${kappa}B$</TEX>), cyclooxygenase-2 (COX-2) and B-cell lymphoma-2 (Bcl-2) gene expression levels was investigated in rat mammary gland carcinogenesis induced by 7,12 dimethylbenz(<TEX>${alpha}$</TEX>)anthracene (DMBA). DMBA increased NF-<TEX>${kappa}B$</TEX>, COX-2 and Bcl-2 gene expression levels and lipid peroxidation (LP), while, decreased glutathione-S-transferase (GST) and superoxide dismutase (SOD) activities and total antioxidant concentration (TAC) compared to the control group. After DMBA administration, SE treatment reduced NF-<TEX>${kappa}B$</TEX>, COX-2 and Bcl-2 gene expression levels and LP. Hence, SE treatment reduced inflammation and cell proliferation, while increasing apoptosis, GST and SOD activities and TAC. Analysis revealed that SE has high concentrations of total flavonoids, triterpenoids, alkaloids and polyphenolic compounds such as gallic, chlorogenic, caffeic, 3,4-dicaffeoyl quinic, 3,5-dicaffeoyl quinic, tannic, cinnamic acids, catechin and phloridzin. These findings indicate that SE may be considered a promising natural product from cruciferous vegetables against breast cancer, especially given its high antioxidant properties." @default.
- W2346644876 created "2016-06-24" @default.
- W2346644876 creator A5014442950 @default.
- W2346644876 creator A5021410996 @default.
- W2346644876 creator A5046891754 @default.
- W2346644876 creator A5050163041 @default.
- W2346644876 creator A5061019646 @default.
- W2346644876 creator A5064310163 @default.
- W2346644876 date "2016-01-11" @default.
- W2346644876 modified "2023-09-30" @default.
- W2346644876 title "Inhibition of NF-ĸB, Bcl-2 and COX-2 Gene Expression by an Extract of Eruca sativa Seeds during Rat Mammary Gland Carcinogenesis" @default.
- W2346644876 cites W1506043065 @default.
- W2346644876 cites W1969675634 @default.
- W2346644876 cites W1983310681 @default.
- W2346644876 cites W1990460129 @default.
- W2346644876 cites W1990802782 @default.
- W2346644876 cites W1991775006 @default.
- W2346644876 cites W2002966962 @default.
- W2346644876 cites W2013676263 @default.
- W2346644876 cites W2013845759 @default.
- W2346644876 cites W2021995332 @default.
- W2346644876 cites W2022971595 @default.
- W2346644876 cites W2034872538 @default.
- W2346644876 cites W2043733949 @default.
- W2346644876 cites W2048041008 @default.
- W2346644876 cites W2055901084 @default.
- W2346644876 cites W2107329907 @default.
- W2346644876 cites W2125070171 @default.
- W2346644876 cites W2133848791 @default.
- W2346644876 cites W2154516093 @default.
- W2346644876 cites W2263023695 @default.
- W2346644876 cites W4245177871 @default.
- W2346644876 doi "https://doi.org/10.7314/apjcp.2015.16.18.8411" @default.
- W2346644876 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26745094" @default.
- W2346644876 hasPublicationYear "2016" @default.
- W2346644876 type Work @default.
- W2346644876 sameAs 2346644876 @default.
- W2346644876 citedByCount "15" @default.
- W2346644876 countsByYear W23466448762016 @default.
- W2346644876 countsByYear W23466448762017 @default.
- W2346644876 countsByYear W23466448762018 @default.
- W2346644876 countsByYear W23466448762019 @default.
- W2346644876 countsByYear W23466448762020 @default.
- W2346644876 countsByYear W23466448762022 @default.
- W2346644876 countsByYear W23466448762023 @default.
- W2346644876 crossrefType "journal-article" @default.
- W2346644876 hasAuthorship W2346644876A5014442950 @default.
- W2346644876 hasAuthorship W2346644876A5021410996 @default.
- W2346644876 hasAuthorship W2346644876A5046891754 @default.
- W2346644876 hasAuthorship W2346644876A5050163041 @default.
- W2346644876 hasAuthorship W2346644876A5061019646 @default.
- W2346644876 hasAuthorship W2346644876A5064310163 @default.
- W2346644876 hasBestOaLocation W23466448761 @default.
- W2346644876 hasConcept C104317684 @default.
- W2346644876 hasConcept C185592680 @default.
- W2346644876 hasConcept C2775838275 @default.
- W2346644876 hasConcept C2778004101 @default.
- W2346644876 hasConcept C2778938436 @default.
- W2346644876 hasConcept C2780829032 @default.
- W2346644876 hasConcept C55493867 @default.
- W2346644876 hasConcept C555283112 @default.
- W2346644876 hasConcept C86803240 @default.
- W2346644876 hasConcept C98274493 @default.
- W2346644876 hasConceptScore W2346644876C104317684 @default.
- W2346644876 hasConceptScore W2346644876C185592680 @default.
- W2346644876 hasConceptScore W2346644876C2775838275 @default.
- W2346644876 hasConceptScore W2346644876C2778004101 @default.
- W2346644876 hasConceptScore W2346644876C2778938436 @default.
- W2346644876 hasConceptScore W2346644876C2780829032 @default.
- W2346644876 hasConceptScore W2346644876C55493867 @default.
- W2346644876 hasConceptScore W2346644876C555283112 @default.
- W2346644876 hasConceptScore W2346644876C86803240 @default.
- W2346644876 hasConceptScore W2346644876C98274493 @default.
- W2346644876 hasIssue "18" @default.
- W2346644876 hasLocation W23466448761 @default.
- W2346644876 hasLocation W23466448762 @default.
- W2346644876 hasOpenAccess W2346644876 @default.
- W2346644876 hasPrimaryLocation W23466448761 @default.
- W2346644876 hasRelatedWork W1997751979 @default.
- W2346644876 hasRelatedWork W2107274226 @default.
- W2346644876 hasRelatedWork W2188617220 @default.
- W2346644876 hasRelatedWork W2315670528 @default.
- W2346644876 hasRelatedWork W2342309179 @default.
- W2346644876 hasRelatedWork W2380016105 @default.
- W2346644876 hasRelatedWork W2430757080 @default.
- W2346644876 hasRelatedWork W2601733601 @default.
- W2346644876 hasRelatedWork W1501884141 @default.
- W2346644876 hasRelatedWork W1519006945 @default.
- W2346644876 hasVolume "16" @default.
- W2346644876 isParatext "false" @default.
- W2346644876 isRetracted "false" @default.
- W2346644876 magId "2346644876" @default.
- W2346644876 workType "article" @default.