FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2346889844> ?p ?o ?g. }

• W2346889844 abstract "The ability to store, integrate, and manipulate information declines with aging. These changes occur earlier, faster, and to a greater degree as a result of neurodegeneration. One of the most common and early characteristics of cognitive decline is difficulty with comprehension of information. The neural mechanisms underlying this breakdown of information processing are poorly understood. Using functional MRI and natural stimuli (e.g., stories), we mapped the neural mechanisms by which the human brain accumulates and processes information with increasing duration and complexity in participants with amnestic mild cognitive impairment (aMCI) and healthy older adults. To explore the mechanisms of information processing, we measured the reliability of brain responses elicited by listening to different versions of a narrated story created by segmenting the story into words, sentences, and paragraphs and then scrambling the segments. Comparing healthy older adults and participants with aMCI revealed that in both groups, all types of stimuli similarly recruited primary auditory areas. However, prominent differences between groups were found at the level of processing long and complex stimuli. In healthy older adults, parietal and frontal regions demonstrated highly synchronized responses in both the paragraph and full story conditions, as has been previously reported in young adults. Participants with aMCI, however, exhibited a robust functional shift of long time scale processing to the pre- and post-central sulci. Our results suggest that participants with aMCI experienced a functional shift of higher order auditory information processing, possibly reflecting a functional response to concurrent or impending neuronal or synaptic loss. This observation might assist in understanding mechanisms of cognitive decline in aMCI." @default.
• W2346889844 created "2016-06-24" @default.
• W2346889844 creator A5006427322 @default.
• W2346889844 creator A5010089445 @default.
• W2346889844 creator A5039274182 @default.
• W2346889844 creator A5043568009 @default.
• W2346889844 creator A5063798638 @default.
• W2346889844 creator A5071098162 @default.
• W2346889844 date "2016-07-13" @default.
• W2346889844 modified "2023-09-26" @default.
• W2346889844 title "Altered Topology in Information Processing of a Narrated Story in Older Adults with Mild Cognitive Impairment" @default.
• W2346889844 cites W1507893557 @default.
• W2346889844 cites W1514308014 @default.
• W2346889844 cites W1559787775 @default.
• W2346889844 cites W1745029452 @default.
• W2346889844 cites W1855610705 @default.
• W2346889844 cites W1963487177 @default.
• W2346889844 cites W1968010387 @default.
• W2346889844 cites W1972009531 @default.
• W2346889844 cites W1972165090 @default.
• W2346889844 cites W1989217296 @default.
• W2346889844 cites W1990207779 @default.
• W2346889844 cites W1991825895 @default.
• W2346889844 cites W2004293194 @default.
• W2346889844 cites W2007997142 @default.
• W2346889844 cites W2012437345 @default.
• W2346889844 cites W2018523864 @default.
• W2346889844 cites W2021720310 @default.
• W2346889844 cites W2025296327 @default.
• W2346889844 cites W2028436804 @default.
• W2346889844 cites W2028524339 @default.
• W2346889844 cites W2035742535 @default.
• W2346889844 cites W2040853845 @default.
• W2346889844 cites W2045867209 @default.
• W2346889844 cites W2048740905 @default.
• W2346889844 cites W2052530454 @default.
• W2346889844 cites W2052742260 @default.
• W2346889844 cites W2053145173 @default.
• W2346889844 cites W2054899104 @default.
• W2346889844 cites W2055649795 @default.
• W2346889844 cites W2061424892 @default.
• W2346889844 cites W2067140282 @default.
• W2346889844 cites W2073441088 @default.
• W2346889844 cites W2079082269 @default.
• W2346889844 cites W2081481111 @default.
• W2346889844 cites W2086216368 @default.
• W2346889844 cites W2087264614 @default.
• W2346889844 cites W2089744719 @default.
• W2346889844 cites W2097214564 @default.
• W2346889844 cites W2103777483 @default.
• W2346889844 cites W2105843706 @default.
• W2346889844 cites W2108452713 @default.
• W2346889844 cites W2111613011 @default.
• W2346889844 cites W2112287510 @default.
• W2346889844 cites W2113319997 @default.
• W2346889844 cites W2113708991 @default.
• W2346889844 cites W2132766843 @default.
• W2346889844 cites W2133331783 @default.
• W2346889844 cites W2135331581 @default.
• W2346889844 cites W2137554996 @default.
• W2346889844 cites W2139784227 @default.
• W2346889844 cites W2148079076 @default.
• W2346889844 cites W2148373393 @default.
• W2346889844 cites W2151721316 @default.
• W2346889844 cites W2157359489 @default.
• W2346889844 cites W2158592797 @default.
• W2346889844 cites W2159178995 @default.
• W2346889844 cites W2159320983 @default.
• W2346889844 cites W2161220328 @default.
• W2346889844 cites W2163274894 @default.
• W2346889844 cites W2165706652 @default.
• W2346889844 cites W2165758561 @default.
• W2346889844 cites W2582524520 @default.
• W2346889844 doi "https://doi.org/10.3233/jad-150845" @default.
• W2346889844 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27163799" @default.
• W2346889844 hasPublicationYear "2016" @default.
• W2346889844 type Work @default.
• W2346889844 sameAs 2346889844 @default.
• W2346889844 citedByCount "5" @default.
• W2346889844 countsByYear W23468898442018 @default.
• W2346889844 countsByYear W23468898442019 @default.
• W2346889844 countsByYear W23468898442021 @default.
• W2346889844 countsByYear W23468898442022 @default.
• W2346889844 crossrefType "journal-article" @default.
• W2346889844 hasAuthorship W2346889844A5006427322 @default.
• W2346889844 hasAuthorship W2346889844A5010089445 @default.
• W2346889844 hasAuthorship W2346889844A5039274182 @default.
• W2346889844 hasAuthorship W2346889844A5043568009 @default.
• W2346889844 hasAuthorship W2346889844A5063798638 @default.
• W2346889844 hasAuthorship W2346889844A5071098162 @default.
• W2346889844 hasConcept C15744967 @default.
• W2346889844 hasConcept C169760540 @default.
• W2346889844 hasConcept C169900460 @default.
• W2346889844 hasConcept C177291462 @default.
• W2346889844 hasConcept C17744445 @default.
• W2346889844 hasConcept C180747234 @default.
• W2346889844 hasConcept C199539241 @default.
• W2346889844 hasConcept C2779226451 @default.
• W2346889844 hasConcept C46312422 @default.
• W2346889844 hasConcept C548259974 @default.

• next