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- W2346971691 endingPage "633" @default.
- W2346971691 startingPage "617" @default.
- W2346971691 abstract "There is a very high prevalence of vitamin D deficiency, which is defined by a serum level of 25-hydroxyvitamin D [25(OH)D] of lower than 20 ng/mL, in all populations of the world. Unfortunately, the prevalence of vitamin D deficiency in patients with intestinal malabsorption syndromes, including cystic fibrosis (CF), celiac disease (CD), short bowel syndrome and inflammatory bowel disease (IBD), is higher than that in the general population, indicating the presence of disease-specific causative factors. In this review, we aimed to present clinical findings to highlight the roles of insufficient exposure to sunlight and inflammation in the development of vitamin D deficiency in patients with intestinal malabsorption syndromes. Furthermore, we aimed to present experimental evidence that supported a role of vitamin D deficiency in the pathogenesis of IBD. Finally, we reviewed clinical intervention strategies aiming to normalize vitamin D status in and even to improve the conditions of patients and to discuss certain issues that needed to be addressed in future research." @default.
- W2346971691 created "2016-06-24" @default.
- W2346971691 creator A5019965651 @default.
- W2346971691 creator A5021445664 @default.
- W2346971691 creator A5035995941 @default.
- W2346971691 creator A5081088557 @default.
- W2346971691 date "2015-11-01" @default.
- W2346971691 modified "2023-10-18" @default.
- W2346971691 title "Vitamin D deficiency in patients with intestinal malabsorption syndromes - think in and outside the gut" @default.
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