Matches in SemOpenAlex for { <https://semopenalex.org/work/W2347029776> ?p ?o ?g. }
- W2347029776 abstract "A misguided inflammatory response is frequently implicated in myelin damage. Particularly prominent among myelin diseases, multiple sclerosis (MS) is an autoimmune condition, with immune–mediated damage central to its aetiology. Nevertheless, a robust inflammatory response is also essential for the efficient regeneration of myelin sheaths after such injury. Here, we discuss the functions of inflammation that promote remyelination, and how these have been experimentally disentangled from the pathological facets of the immune response. We focus on the contributions that resident microglia and monocyte-derived macrophages make to remyelination and compare the roles of these two populations of innate immune cells. Finally, the current literature is framed in the context of developing therapies that manipulate the innate immune response to promote remyelination in clinical myelin disease." @default.
- W2347029776 created "2016-06-24" @default.
- W2347029776 creator A5013660009 @default.
- W2347029776 creator A5051099517 @default.
- W2347029776 creator A5081242086 @default.
- W2347029776 creator A5084076053 @default.
- W2347029776 date "2016-05-03" @default.
- W2347029776 modified "2023-09-26" @default.
- W2347029776 title "CNS Remyelination and the Innate Immune System" @default.
- W2347029776 cites W1485262693 @default.
- W2347029776 cites W1515592753 @default.
- W2347029776 cites W1523338791 @default.
- W2347029776 cites W1571557003 @default.
- W2347029776 cites W1575907081 @default.
- W2347029776 cites W1594905954 @default.
- W2347029776 cites W1861300743 @default.
- W2347029776 cites W1866034006 @default.
- W2347029776 cites W1937650001 @default.
- W2347029776 cites W1973520165 @default.
- W2347029776 cites W1973971608 @default.
- W2347029776 cites W1977046333 @default.
- W2347029776 cites W1977213877 @default.
- W2347029776 cites W1977631233 @default.
- W2347029776 cites W1980789245 @default.
- W2347029776 cites W1981117271 @default.
- W2347029776 cites W1984891852 @default.
- W2347029776 cites W1987735399 @default.
- W2347029776 cites W1992172737 @default.
- W2347029776 cites W1992759422 @default.
- W2347029776 cites W1995953333 @default.
- W2347029776 cites W1999419270 @default.
- W2347029776 cites W2034957851 @default.
- W2347029776 cites W2036605323 @default.
- W2347029776 cites W2038757125 @default.
- W2347029776 cites W2043200832 @default.
- W2347029776 cites W2043406861 @default.
- W2347029776 cites W2045341846 @default.
- W2347029776 cites W2048082433 @default.
- W2347029776 cites W2050964449 @default.
- W2347029776 cites W2052616119 @default.
- W2347029776 cites W2054536322 @default.
- W2347029776 cites W2061771806 @default.
- W2347029776 cites W2062326815 @default.
- W2347029776 cites W2067453766 @default.
- W2347029776 cites W2071611370 @default.
- W2347029776 cites W2077492083 @default.
- W2347029776 cites W2081583081 @default.
- W2347029776 cites W2083218881 @default.
- W2347029776 cites W2085217436 @default.
- W2347029776 cites W2089851064 @default.
- W2347029776 cites W2094044389 @default.
- W2347029776 cites W2094660330 @default.
- W2347029776 cites W2096423240 @default.
- W2347029776 cites W2099647077 @default.
- W2347029776 cites W2100119722 @default.
- W2347029776 cites W2102628016 @default.
- W2347029776 cites W2103758700 @default.
- W2347029776 cites W2104447446 @default.
- W2347029776 cites W2106980391 @default.
- W2347029776 cites W2111256919 @default.
- W2347029776 cites W2111428020 @default.
- W2347029776 cites W2122587876 @default.
- W2347029776 cites W2124836944 @default.
- W2347029776 cites W2132924600 @default.
- W2347029776 cites W2141812010 @default.
- W2347029776 cites W2142808413 @default.
- W2347029776 cites W2145533845 @default.
- W2347029776 cites W2148898943 @default.
- W2347029776 cites W2152131288 @default.
- W2347029776 cites W2155490506 @default.
- W2347029776 cites W2158151457 @default.
- W2347029776 cites W2159443316 @default.
- W2347029776 cites W2159560463 @default.
- W2347029776 cites W2162477292 @default.
- W2347029776 cites W2163410184 @default.
- W2347029776 cites W2168203604 @default.
- W2347029776 cites W2169924875 @default.
- W2347029776 cites W2171467864 @default.
- W2347029776 cites W2174701285 @default.
- W2347029776 cites W2280077905 @default.
- W2347029776 cites W246675750 @default.
- W2347029776 cites W4241890711 @default.
- W2347029776 cites W4378744619 @default.
- W2347029776 doi "https://doi.org/10.3389/fcell.2016.00038" @default.
- W2347029776 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4853384" @default.
- W2347029776 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27200350" @default.
- W2347029776 hasPublicationYear "2016" @default.
- W2347029776 type Work @default.
- W2347029776 sameAs 2347029776 @default.
- W2347029776 citedByCount "42" @default.
- W2347029776 countsByYear W23470297762016 @default.
- W2347029776 countsByYear W23470297762017 @default.
- W2347029776 countsByYear W23470297762018 @default.
- W2347029776 countsByYear W23470297762019 @default.
- W2347029776 countsByYear W23470297762020 @default.
- W2347029776 countsByYear W23470297762021 @default.
- W2347029776 countsByYear W23470297762022 @default.
- W2347029776 countsByYear W23470297762023 @default.
- W2347029776 crossrefType "journal-article" @default.
- W2347029776 hasAuthorship W2347029776A5013660009 @default.