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• W2347143901 abstract "Haemodynamic simulations using one-dimensional (1-D) computational models exhibit many of the features of the systemic circulation under normal and diseased conditions. We propose a novel linear 1-D dynamical theory of blood flow in networks of flexible vessels that is based on a generalized Darcy’s model and for which a full analytical solution exists in frequency domain. We assess the accuracy of this formulation in a series of benchmark test cases for which computational 1-D and 3-D solutions are available. Accordingly, we calculate blood flow and pressure waves, and velocity profiles in the human common carotid artery, upper thoracic aorta, aortic bifurcation, and a 20-artery model of the aorta and its larger branches. Our analytical solution is in good agreement with the available solutions and reproduces the main features of pulse waveforms in networks of large arteries under normal physiological conditions. Our model reduces computational time and provides a new approach for studying arterial pulse wave mechanics; e.g., the analyticity of our model allows for a direct identification of the role played by physical properties of the cardiovascular system on the pressure waves." @default.
• W2347143901 created "2016-06-24" @default.
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• W2347143901 date "2016-05-02" @default.
• W2347143901 modified "2023-10-02" @default.
• W2347143901 title "A Novel Analytical Approach to Pulsatile Blood Flow in the Arterial Network" @default.
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• W2347143901 doi "https://doi.org/10.1007/s10439-016-1625-3" @default.
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• W2347143901 hasPublicationYear "2016" @default.
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