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• W2347264225 abstract "Objective:To study the clinical value of unenhanced MRI in combination with diffusion-weighted imaging(DWI)in the diagnosis of rectal carcinoma.Methods:28patients with rectal carcinoma underwent unenhanced MRI and DWI were retrospectively studied,to evaluate the tumor morphology,tumor staging(T-stage),lymph node metastases,circumferential resection margin(CRM)status,distance between lower edge of the tumor and the anal verge and correlated with pathology.The consistency of MRI and pathology on T-staging,N-staging and CRM involvement was evaluated by Kappa test.Results:Unenhanced MRI and DWI could accurately show the tumor location and morphology.The overall Tstaging accuracy of 28 cases was 78.57%(22/28).The accuracy of stage T1~T2,T3 and T4 was 85.71%,78.57% and92.86% respectively.Statistical analysis showed that MRI and pathology for T-staging had a high degree of consistency(Kappa=0.656,P=0.000).The diagnosis accuracy of N-staging using MRI in combination with DWI was 71.43%(20/28).The sensitivity and specificity to determine lymph node metastasis was 66.67%(6/9)and 73.68%(14/19)respectively.Statistical analysis also showed that MRI and pathology for N-staging had intermediate consistency.The overall determination accuracy in CRM state was 85.71%(24/28).The sensitivity and specificity was 90.90%(10/11)and82.35%(14/17)respectively.The positive and negative predictive values was 76.92%(10/13)and 93.33%(14/15)respectivly.MRI and pathology assessment in the involvement of circumferential resection margin had high degree of consistency(Kappa=0.710,P=0.000).Curved distances between the lower edge of the tumor and the anal verge could be clearly measured on sagittal MRI images in 18 cases.Conclusion:Unenhanced MRI scan in combination with DWI was of important clinical significance in the diagnosis,T-staging,circumferential resection margin(CRM)status and distance measurement between lower edge of the tumor and the anal verge of rectal carcinoma." @default.
• W2347264225 created "2016-06-24" @default.
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• W2347264225 date "2015-01-01" @default.
• W2347264225 modified "2023-09-28" @default.
• W2347264225 title "Clinical application of unenhanced MRI in combination with diffusion-weighted imaging in the diagnosis of rectal carcinoma" @default.
• W2347264225 hasPublicationYear "2015" @default.
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