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- W2347266614 abstract "Based on the structure of 5-fluoroindol-2-one and fragments from thirteen multi-target tyrosine kinase inhibitors which have been marketed or in the phase of clinical research, eleven 3-aromatic Shiff base-5-fluoroindol-2-one derivatives were designed and synthesized. Their structures were identified by 1H NMR, MS and elemental analysis. In vitro antitumor bioactivities evaluation was done by MTT method. It was shown that most of synthesized compounds had antitumor activities and compounds 1b, 1g, 1i and 1h were better than or equal to the antitumor activity of positive control." @default.
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- W2347266614 date "2011-11-01" @default.
- W2347266614 modified "2023-09-23" @default.
- W2347266614 title "[Synthesis and biological evaluation of 3-aromatic Shiff base-5-fluoroindol-2-one derivatives]." @default.
- W2347266614 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22260025" @default.
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