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- W2347308333 abstract "Objective To analyze the clinical value of a passive particle agglutination(PPA)assay and enzyme-linked immunosorbent assay(ELISA)in detecting Mycoplasma pneumoniae in adult patients with pneumonia Methods PPA and ELISA were used to detect M.pneumoniae antibodies and specific M.pneumoniaeIgA,IgM,and IgG antibodies in90 serum samples from adults with community-acquired pneumonia(CAP).The results were analyzed statistically. Results Samples tested positive for M.pneumoniae antibodies at a rate of 72.2%(65/90)according to PPA.Samples tested positive for M.pneumoniae antibodies at a rate of 50%(45/90)according to ELISA.A chi-squared test revealed a significant difference in positivity for M.pneumoniae antibodies for the two methods(P0.05).Samples tested positive for M.pneumoniae IgA at a rate of 26.7%(24/90)and positive for M.pneumoniae IgM at a rate of 22.2%(20/90).There were no significant differences in positivity for M.pneumoniae IgA and IgM(P0.05),and the result was consistent(Kappa=0.520).Samples tested positive for M.pneumoniae IgG at a rate of 37.8%(34/90),and this rate was significantly higher than the rates for M.Pneumoniae IgA and IgM(P0.05).Samples increasingly tested positive for M.pneumoniae IgA and IgM as the PPA titer rose. Methods(P0.05).The positive rate of MP-IgA was 26.7%(24/90),the positive rate of MP-IgM was 22.2%(20/90).There was no significant difference between the positive rate of MP-IgA and MP-IgM(P0.05),and the result had consistency(Kappa=0.520).The positive rate of MP-IgG was37.8%(34/90),and it was significantly higher than the MP-IgA and MP-IgM(P0.05).The positive rates of MP-IgA and MP-IgM were increased with the PPA titers. Conclusion This study demonstrated that detection of M.pneumoniae IgA,IgM,and IgG with ELISA and detection of M.pneumoniae antibodies with PPA can improve the accuracy of the laboratory diagnosis of CAP.This combined detection has clinical significance in terms of the early diagnosis of M.pneumoniaeinfections in adults." @default.
- W2347308333 created "2016-06-24" @default.
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- W2347308333 date "2014-01-01" @default.
- W2347308333 modified "2023-09-27" @default.
- W2347308333 title "Comparison of the clinical value of a passive agglutination assay and ELISA at detecting Mycoplasma pneumoniae in adults" @default.
- W2347308333 hasPublicationYear "2014" @default.
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