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- W2347323014 abstract "Objective The aims of this study were to investigate the characteristics of cognitive function in patients with Type 2 diabetes(DM) and their relationships with the plasma levels of cortisol.Methods 89 patients with Type 2 DM and 40 nondiabetic controls with ages and education levels matched were included in this study,all the subjects have received a set of multi-dimension neuropsychologic tests for the cognitive assessment.A radioimmunoassay was used to measure plasma cortisol concentrations.Results (1)The performances of type 2 DM group in the Trial marking test B(TMT B),the delayed recall of auditory verbal learning test(AVLT-DR),the symbol digit modulation test(SDMT),verbal fluency test(VFT) and clock drawing test(CDT) are obviously worse than those of controls group(P0.01).(2)The plasma levels of cortisol in DM group is significantly higher than those in controls group(P0.05).In both control and whole group,the plasma levels of cotisol show negtive correlation with the scores of CDT(R=-0.356,P=0.024;R=-0.219,P=0.012),but in type 2 DM group the correlation analysis between plasma levels of cortisol and scores of each neuropsy-chological test gets no positive result(P0.05).Conclusions Patients with Type 2 DM prone to have multi-domain cognitive impairments,with a higher plasma levels of cortisol accompanied.But the plasma levels of cortisol seem to have no correlation with cognitive function in type 2 DM" @default.
- W2347323014 created "2016-06-24" @default.
- W2347323014 creator A5091708029 @default.
- W2347323014 date "2009-01-01" @default.
- W2347323014 modified "2023-09-23" @default.
- W2347323014 title "Characteristics of cognition and plasma levels of cortisol in geratic patients with type 2 diabetes" @default.
- W2347323014 hasPublicationYear "2009" @default.
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