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- W2347351766 abstract "Objective To compare the effects of dexmedetomidine and midazolam in elderly vitreous surgery.Methods Forty elder patients underwent vitreous surgery under peribulbar anaesthesia were randomly divided into dexmedetomidine group(20 cases) and midazolam group(20 cases),the patients in two groups received dexmedetomidine and midazolam in surgery,respectively.Mean arterial pressure(MAP),heart rate(HR),Ramsay sedation score and visual analogue scale(VAS) of two groups were observed and compared.Results Compared with pre-anaesthesia,MAP and HR at different time points in surgery of dexmedetomidine group were significant decreased,there were statistical difference(both P0.05),while which of midazolam group were significant increased,there were statistical difference(both P0.05).Compared with pre-anaesthesia,Ramsay sedation score at different time points in surgery of two groups were increased,there was no stiatistical difference between two groups(P0.05).No patient in dexmedetomidine group received fentanyl,no restlessness appeared;while 14 cases in midazolam group received fentanyl,3 cases with respiratory depression needed the temporary artificial ventilation to maintain the SpO2 in normal level,6 cases were with restlessness.Conclusion Dexmedetomidine is safe and effective in the elderly vitreous surgery,which is worthy for widely application." @default.
- W2347351766 created "2016-06-24" @default.
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- W2347351766 date "2012-01-01" @default.
- W2347351766 modified "2023-09-28" @default.
- W2347351766 title "Comparision of dexmedetomidine and midazolam in elderly vitreous surgery" @default.
- W2347351766 hasPublicationYear "2012" @default.
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