Matches in SemOpenAlex for { <https://semopenalex.org/work/W2347486520> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W2347486520 abstract "Objective The study was to observe the delaying of atherosclerotic(AS)plaque formation in rabbit fed with high lipid diet by Huashi Tongyu Buqi Method.Methods Pure bred 18New Zealand male white rabbits(4months old)were experimental subjects.After normal feeding for one week,the rats were changed to high lipid diet(1% cholesterol+ 6% yolk powder + 8% lard +85% basic fodder),and they were randomly divided into three groups:six rabbits in control group(without using any drugs),six rabbits in Chinese medicine group(Heye,Zexie,Huzhang,etc)and six rabbits in western medicine group(aspirin+ atorvastatin+ probucol)and observed for three months.After three months,auricular venous blood of each group was drawn and total cholesterol(TC),triglycerides(TG),low-density lipoprotein-cholesterol(LDL-C),serum matrix metalloprotinase-9(MMP-9),malondialdehyde(MDA)and ox-LDL were measured,and then rabbits were killed to get aorta.Hematoxylin-eosinstaining and immunohistochemistry staining were used to observe the histopathological changes of aorta,atherosclerotic plaque area,intima and vessel wall thickness.Results TC,TG and LDL-C of Chinese medicine group and western medicine group were significantly lower than those of control group(P0.01),respectively TC(2.39±0.15)mmol/L,(2.08±0.12)mmol/L vs(13.02±0.20)mmol/L;TG(2.58±0.16)mmol/L,(1.90±0.08)mmol/L vs(11.08±0.19)mmol/L;LDL-C(1.05±0.24)mmol/L,(0.85±0.09)mmol/L vs(10.13±0.20)mmol/L,TC and TG of western medicine group was much lower than that of Chinese medicine group(P0.01);MDA,MMP-9and ox-LDL level as compared with control were decreased by different extents(P 0.01).Aortic intima thickness of Chinese medicine group and western medicine group decreased significantly as compared with that of control group,(12.28±1.28)μm,(5.20±0.81)μm vs(40.06±3.94)μm(P 0.01),while aortic intima thickness of western medicine group showed more decrease.Conclusion Huashi Tongyu Buqi method delays the atherosclerotic plaque formation in rabbit,decreases blood LDL-C,provides new research theoretical evidence for Chinese medicine and atherosclerosis." @default.
- W2347486520 created "2016-06-24" @default.
- W2347486520 creator A5051287665 @default.
- W2347486520 date "2013-01-01" @default.
- W2347486520 modified "2023-09-28" @default.
- W2347486520 title "Experimental study on delaying atherosclerotic plaque formation in rabbit by Huashi Tongyu Buqi method" @default.
- W2347486520 hasPublicationYear "2013" @default.
- W2347486520 type Work @default.
- W2347486520 sameAs 2347486520 @default.
- W2347486520 citedByCount "0" @default.
- W2347486520 crossrefType "journal-article" @default.
- W2347486520 hasAuthorship W2347486520A5051287665 @default.
- W2347486520 hasConcept C125473707 @default.
- W2347486520 hasConcept C126322002 @default.
- W2347486520 hasConcept C134018914 @default.
- W2347486520 hasConcept C139572402 @default.
- W2347486520 hasConcept C142724271 @default.
- W2347486520 hasConcept C151730666 @default.
- W2347486520 hasConcept C204232928 @default.
- W2347486520 hasConcept C2776151105 @default.
- W2347486520 hasConcept C2776167589 @default.
- W2347486520 hasConcept C2776393769 @default.
- W2347486520 hasConcept C2777482532 @default.
- W2347486520 hasConcept C2778163477 @default.
- W2347486520 hasConcept C2778401633 @default.
- W2347486520 hasConcept C2779091943 @default.
- W2347486520 hasConcept C2779980429 @default.
- W2347486520 hasConcept C2780886939 @default.
- W2347486520 hasConcept C555293320 @default.
- W2347486520 hasConcept C64837602 @default.
- W2347486520 hasConcept C71924100 @default.
- W2347486520 hasConcept C74864618 @default.
- W2347486520 hasConcept C86803240 @default.
- W2347486520 hasConceptScore W2347486520C125473707 @default.
- W2347486520 hasConceptScore W2347486520C126322002 @default.
- W2347486520 hasConceptScore W2347486520C134018914 @default.
- W2347486520 hasConceptScore W2347486520C139572402 @default.
- W2347486520 hasConceptScore W2347486520C142724271 @default.
- W2347486520 hasConceptScore W2347486520C151730666 @default.
- W2347486520 hasConceptScore W2347486520C204232928 @default.
- W2347486520 hasConceptScore W2347486520C2776151105 @default.
- W2347486520 hasConceptScore W2347486520C2776167589 @default.
- W2347486520 hasConceptScore W2347486520C2776393769 @default.
- W2347486520 hasConceptScore W2347486520C2777482532 @default.
- W2347486520 hasConceptScore W2347486520C2778163477 @default.
- W2347486520 hasConceptScore W2347486520C2778401633 @default.
- W2347486520 hasConceptScore W2347486520C2779091943 @default.
- W2347486520 hasConceptScore W2347486520C2779980429 @default.
- W2347486520 hasConceptScore W2347486520C2780886939 @default.
- W2347486520 hasConceptScore W2347486520C555293320 @default.
- W2347486520 hasConceptScore W2347486520C64837602 @default.
- W2347486520 hasConceptScore W2347486520C71924100 @default.
- W2347486520 hasConceptScore W2347486520C74864618 @default.
- W2347486520 hasConceptScore W2347486520C86803240 @default.
- W2347486520 hasLocation W23474865201 @default.
- W2347486520 hasOpenAccess W2347486520 @default.
- W2347486520 hasPrimaryLocation W23474865201 @default.
- W2347486520 hasRelatedWork W2240121820 @default.
- W2347486520 hasRelatedWork W2348518862 @default.
- W2347486520 hasRelatedWork W2353620648 @default.
- W2347486520 hasRelatedWork W2359235994 @default.
- W2347486520 hasRelatedWork W2360142251 @default.
- W2347486520 hasRelatedWork W2361789869 @default.
- W2347486520 hasRelatedWork W2363533766 @default.
- W2347486520 hasRelatedWork W2369334933 @default.
- W2347486520 hasRelatedWork W2373258466 @default.
- W2347486520 hasRelatedWork W2377550867 @default.
- W2347486520 hasRelatedWork W2377960496 @default.
- W2347486520 hasRelatedWork W2379134011 @default.
- W2347486520 hasRelatedWork W2380529055 @default.
- W2347486520 hasRelatedWork W2383426582 @default.
- W2347486520 hasRelatedWork W2385951734 @default.
- W2347486520 hasRelatedWork W2387834166 @default.
- W2347486520 hasRelatedWork W2388360743 @default.
- W2347486520 hasRelatedWork W2392179038 @default.
- W2347486520 hasRelatedWork W2393424487 @default.
- W2347486520 hasRelatedWork W2394414116 @default.
- W2347486520 isParatext "false" @default.
- W2347486520 isRetracted "false" @default.
- W2347486520 magId "2347486520" @default.
- W2347486520 workType "article" @default.