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- W2347603920 abstract "Objective To observe the clinical efficacy and safety of photodynamic therapy using 5-aminolevulinic acid(ALA-PDT) in the treatment of acne vulgaris.Methods Ninety patients with moderate to severe facial acne were randomly divided into two groups with single-blind method,45 cases in treatment group were given ALA-PDT to the facial lesions for 2-4 times with an interval of 10 days,the other 45 cases in control group received oral isotretinoin,10mg twice daily for 40 days.The patients were evaluated for efficacy on days 10,20,30 and 40 after the initial treatment.The side-effects were also recorded during the treatment.Results The total effective rate was 97.8% in treatment group after 2-4 times of treatment,77.8% in the control group and the curative effect in treatment group was significantly better than that in control groups(P0.01).The lesions tended to recur more slightly with a longer remission period in treatment group than in the control group.Every kind of lesions,including comedo,papules,pustules,cyst and nodules were significant reduced too.Conclusion The curative effect of ALA-PDT is better than that of oral isotretinoin.ALA-PDT is a simple,effective and optional treatment for moderate to severe acne with few adverse reactions." @default.
- W2347603920 created "2016-06-24" @default.
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- W2347603920 date "2012-01-01" @default.
- W2347603920 modified "2023-09-26" @default.
- W2347603920 title "Clinical observation of photodynamic therapy with 5-aminolevulinic acid in the treatment of acne vulgaris" @default.
- W2347603920 hasPublicationYear "2012" @default.
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