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- W2347617249 abstract "Objective To explore the relationship between age,high sensitivity C-reactive protein (hs-CRP) level and changes of sex hormone levels in postmenopausal women with coronary heart disease(CHD).Methods 362 postmenopausal women(menopause≥1 year) were studied and divided into CHD group(127 cases) and control group(235 cases) according to the result of coronary angiography.Then the cases were divided into three groups according to age:107 patients were ≤60 years old,113 patients were 61 — 70 years old and 142 patients were 70 years.Plasma levels of estradiol(E_2),testosterone(T),follicular estrogen,luteinizing hormone,blood lipids and hs-CRP were examined.The relationship of sex hormone with hs-CRP in different age groups were analysed and compared.Results Compared with the control cases of the same age group, significantly lower E_2 level and E_2/T ratio,higher T level were observed in CHD patients≤60 years old (P 0.05 ,P _ 0.01) ,while the level of hs-CRP was significantly higher in CHD patients 60 years old (P 0.01).The difference in sex hormone level was not statistically significent. Linear regression analysis showed that sex hormone levels were negatively correlated with age and positively correlated with BMI (P0.05,P 0.01).After adjusted for age and BMI,sex hormone level was not correlated with hs-CRP.Logistic regression analysis showed that E_2 was an important protective factor for CHD (P 0.01).Conclusion The prevention and treatment strategies in postmenopausal women of different ages should be different." @default.
- W2347617249 created "2016-06-24" @default.
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- W2347617249 date "2010-01-01" @default.
- W2347617249 modified "2023-09-23" @default.
- W2347617249 title "Study on relationship between age,hs-CRP level and sex hormone in postmenopausal women with coronary artery disease" @default.
- W2347617249 hasPublicationYear "2010" @default.
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