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- W2347624385 abstract "Aim To search antifungal and anticancer constituents of Eleutherine americana Merr.et K.Heyne(Hong-cong).Method Pyricularia oryzae bioassa guided isolation was used for screening bioactive constituents of Eleutherine americana.Results and conclusion Ten compounds were obtained and identified as isoeleutherol(1),isoeleutherin(2),eleutherin(3),β-sitosterol(4),8-hydroxy-3,4-dimethoxy-1-methyl-anthraquinone-2-carboxylic acid methyl ester(5),4-hydroxyeleutherin(6),hongconin(7),4,8-dihydroxy-3-methoxy-1-methyl-anthraquinone-2-carboxylic acid methyl ester(8),dihydro-eleutherinol(9),and 1,3,6-trihydroxy-8-methyl anthraquinone(10),respectively by physico-chemical properties and spectral data.These compounds belong to either naphthoquinones,naphthols,or anthraquinones.Compounds 9 and 10 are reported from Eleutherine genus for the first time.Their activities against the growth of Pyricularia oryzae were tested.Some of them showed potential activities on Pyricularia oryzae with MMDC(minimum morphological deformation concentration)value of 30 μmol·L -1(2),30 μmol·L -1(3), 170 μmol·L -1(5),130 μmol·L -1(6),55 μmol·L -1(7),60 μmol·L -1(9)and 150 μmol·L -1(10),respectively.Additionally,MTT method showed some of these compounds could inhibit the proliferation of K562(human erythroleukemia)with IC_ 50 value of 33 μmol·L -1(2),49 μmol·L -1(3),266 μmol·L -1(5),35 μmol·L -1(6), 174 μmol·L -1(7)and 154 μmol·L -1(9)." @default.
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- W2347624385 date "2005-01-01" @default.
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- W2347624385 title "Studies on the antifungal constituents isolated from Eleutherine americana" @default.
- W2347624385 hasPublicationYear "2005" @default.
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