Matches in SemOpenAlex for { <https://semopenalex.org/work/W2347643127> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W2347643127 abstract "Objective To observe the effect of clopidogrel on high sensitive C-reactive protein(hs-CRP) and tumor necrosis factor-α(TNF-α) in patients with acute coronary syndrome(ACS) after percutaneous coronary intervention(PCI). Methods 72 patients with ACS and PCI were randomly divided into two groups,patients in control group(35 cases) took 300 mg aspirin for the first time,then 100 mg aspirin every day,whereas patients in combination group(37 cases) took 300 mg aspirin and 300 mg clopidogrel for the first time,then 100 mg aspirin and 75 mg clopidogrel every day.2 groups were treated for 6 months.hs-CRP and TNF-αwere examined before taking medicine in all patients 10 and 30 days after taking medicine separately;prothrombin time(PT),activated partial thromboplastin time(APTT) and platelet count(PLT) were examined before taking medicine,30 days after taking medicine separately;the occurrence of cardiovascular events and adverse drug reactions within six months were observed.Results The hs-CRP,TNF-αof two groups on 10 days,30 days after treatment were decreased than before treatment(P0.05 or P0.01);the hs-CRP,TNF-αin the combination group on 10 days,30 days after treatment were decreased in combination group than that in the control group(P0.05 or P0.01); the incidence of cardiovascular events within 6 months in the combination group was significandy lower than that in the control group(2.7%vs 22.9%,P0.05);there was no significant difference of PT,APTT and PLT between two groups before treatment and 30 days after treatment(all P0.05 );the incidence of bleeding within 6 months was no significant difference between two groups(16.2%,8.6%,P0.05).Conclusion Clopidogrel can reduce the level of inflammation factors,reduce cardiovascular events.The anti-inflammatory effect of clopidogrel and aspirin were significantly stronger than that of single aspirin without increase the patient bleeding events." @default.
- W2347643127 created "2016-06-24" @default.
- W2347643127 creator A5024792267 @default.
- W2347643127 date "2012-01-01" @default.
- W2347643127 modified "2023-09-23" @default.
- W2347643127 title "Effect of clopidogrel on high sensitive C-reactive protein and tumor necrosis factor-α in patients with acute coronary syndrome after percutaneous coronary intervention" @default.
- W2347643127 hasPublicationYear "2012" @default.
- W2347643127 type Work @default.
- W2347643127 sameAs 2347643127 @default.
- W2347643127 citedByCount "0" @default.
- W2347643127 crossrefType "journal-article" @default.
- W2347643127 hasAuthorship W2347643127A5024792267 @default.
- W2347643127 hasConcept C126322002 @default.
- W2347643127 hasConcept C141071460 @default.
- W2347643127 hasConcept C17991360 @default.
- W2347643127 hasConcept C2777628954 @default.
- W2347643127 hasConcept C2777698277 @default.
- W2347643127 hasConcept C2777849778 @default.
- W2347643127 hasConcept C2778261982 @default.
- W2347643127 hasConcept C2780400711 @default.
- W2347643127 hasConcept C2780434524 @default.
- W2347643127 hasConcept C45393284 @default.
- W2347643127 hasConcept C500558357 @default.
- W2347643127 hasConcept C71924100 @default.
- W2347643127 hasConcept C89560881 @default.
- W2347643127 hasConcept C90924648 @default.
- W2347643127 hasConceptScore W2347643127C126322002 @default.
- W2347643127 hasConceptScore W2347643127C141071460 @default.
- W2347643127 hasConceptScore W2347643127C17991360 @default.
- W2347643127 hasConceptScore W2347643127C2777628954 @default.
- W2347643127 hasConceptScore W2347643127C2777698277 @default.
- W2347643127 hasConceptScore W2347643127C2777849778 @default.
- W2347643127 hasConceptScore W2347643127C2778261982 @default.
- W2347643127 hasConceptScore W2347643127C2780400711 @default.
- W2347643127 hasConceptScore W2347643127C2780434524 @default.
- W2347643127 hasConceptScore W2347643127C45393284 @default.
- W2347643127 hasConceptScore W2347643127C500558357 @default.
- W2347643127 hasConceptScore W2347643127C71924100 @default.
- W2347643127 hasConceptScore W2347643127C89560881 @default.
- W2347643127 hasConceptScore W2347643127C90924648 @default.
- W2347643127 hasLocation W23476431271 @default.
- W2347643127 hasOpenAccess W2347643127 @default.
- W2347643127 hasPrimaryLocation W23476431271 @default.
- W2347643127 hasRelatedWork W1970334542 @default.
- W2347643127 hasRelatedWork W2347667763 @default.
- W2347643127 hasRelatedWork W2348307592 @default.
- W2347643127 hasRelatedWork W2349580432 @default.
- W2347643127 hasRelatedWork W2350951647 @default.
- W2347643127 hasRelatedWork W2351063593 @default.
- W2347643127 hasRelatedWork W2352430258 @default.
- W2347643127 hasRelatedWork W2362311975 @default.
- W2347643127 hasRelatedWork W2369979361 @default.
- W2347643127 hasRelatedWork W2380099191 @default.
- W2347643127 hasRelatedWork W2381235609 @default.
- W2347643127 hasRelatedWork W2382765996 @default.
- W2347643127 hasRelatedWork W2383871907 @default.
- W2347643127 hasRelatedWork W2387593436 @default.
- W2347643127 hasRelatedWork W2388626260 @default.
- W2347643127 hasRelatedWork W2389119000 @default.
- W2347643127 hasRelatedWork W2392655103 @default.
- W2347643127 hasRelatedWork W3031195177 @default.
- W2347643127 hasRelatedWork W3032002504 @default.
- W2347643127 hasRelatedWork W2162886638 @default.
- W2347643127 isParatext "false" @default.
- W2347643127 isRetracted "false" @default.
- W2347643127 magId "2347643127" @default.
- W2347643127 workType "article" @default.